推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
powder
顏色
white to off-white
溶解度
H2O: >30 mg/mL
起源
Sanofi Aventis
儲存溫度
2-8°C
SMILES 字串
O.CS(O)(=O)=O.O=C1CN2[C@@H]3C[C@H](C[C@H]2CC1C3)OC(=O)c4c[nH]c5ccccc45
InChI
1S/C19H20N2O3.CH4O3S.H2O/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17;1-5(2,3)4;/h1-4,9,11-14,20H,5-8,10H2;1H3,(H,2,3,4);1H2/t11?,12-,13+,14+;;
InChI 密鑰
QTFFGPOXNNGTGZ-BHSFMSKKSA-N
生化/生理作用
Dolasetron mesylate hydrate is a highly specific and selective serotonin 5-HT3 receptor antagonist, not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors.
特點和優勢
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
Brain research, 1352, 83-93 (2010-07-20)
The balance between descending inhibition and facilitation is thought to be disturbed in chronic pain states. Increased facilitation by spinally released serotonin has been suggested by demonstration that mechanically evoked neuronal responses of wide dynamic range neurons are inhibited by
Journal of clinical anesthesia, 19(8), 622-625 (2007-12-18)
A 52-year-old woman with hypertension and Graves' disease was scheduled for surgical removal of a meningioma. Intraoperative events were significant for hypotension requiring a vasopressin infusion. Prophylactic dolasetron was administered to the patient before emergence. The patient's trachea was easily
Dolasetron and QT interval.
Emergency medicine journal : EMJ, 25(10), 706-706 (2008-10-10)
Antiemetic agents.
Oncology (Williston Park, N.Y.), 21(8 Suppl), 48-48 (2007-09-12)
[Palonosetron in the prevention of chemotherapy-induced nausea and vomiting (CINV) in Italy: pharmacologic, clinical and economic aspects].
Tumori, 94(2), suppl 26-suppl 32 (2008-06-21)
文章
Sigma-Aldrich offers many products related to serotonin receptors for your research needs.
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