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About This Item
經驗公式（希爾表示法）:
C11H17N4O13P3
CAS號碼:
分子量：:
506.19
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.52
推薦產品
生物源
Porcine muscle
rabbit muscle
品質等級
化驗
≥95% (HPLC)
形狀
liquid
濃度
10 mM in H2O
顏色
colorless
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
NC1=NC(=O)c2ccn(C3CC(O)C(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O3)c2N1
InChI
1S/C11H17N4O13P3/c12-11-13-9-5(10(17)14-11)1-2-15(9)8-3-6(16)7(26-8)4-25-30(21,22)28-31(23,24)27-29(18,19)20/h1-2,6-8,16H,3-4H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,12,13,14,17)
InChI 密鑰
DLLXAZJTLIUPAI-UHFFFAOYSA-N
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應用
7-脱氮-2′-脱氧鸟苷-5′-三磷酸锂盐已用作裂解剂，评估其直接细胞裂解的效率、RNA稳定性，以及在分析少量细胞样品时与下游逆转录定量实时PCR的兼容性。
生化／生理作用
7-脱氮-2′-脱氧鸟苷-5′-三磷酸 (7-deaza-dGTP) 与天然底物 dGTP 竞争并阻断端粒酶活性。该核苷酸掺入端粒后，会即刻改变端粒的二级结构，使端粒酶难以识别它，无法进一步合成端粒。这种dGTP类似物可与常规碱基弱配对，最大限度地减少DNA二级结构的形成，同时成为DNA聚合酶的良好底物。7-deaza-dGTP与二甲基亚砜 (DMSO) 和甜菜碱结合使用可增强富含GC的 DNA 序列的聚合酶链式反应 (PCR) 扩增。
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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