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D6920

Sigma-Aldrich

2′-脱氧腺苷5′-三磷酸 钠盐 溶液

10 mM

同義詞:

dATP

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About This Item

EC號碼:
217-662-3
分類程式碼代碼:
41106305
NACRES:
NA.52

化驗

≥99%

品質等級

200

形狀

liquid

濃度

10 mM

顏色

colorless

異物活動

DNase, RNase, NICKase, none detected

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[Na+].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O3

InChI

1S/C10H16N5O12P3.Na/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19;/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);/q;+1/p-1/t5-,6+,7+;/m0./s1

InChI 密鑰

YJWCICGGRLOGEH-VWZUFWLJSA-M

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相關類別

一般說明

2′-脱氧腺苷5′-三磷酸（dATP）由脱氧核糖上的一个碱基和糖上与一个由三个磷酸残基组成的链相结合的糖上的5′-羟基组成。细胞利用dATP通过DNA聚合酶合成DNA。

應用

2′-脱氧腺苷5′-三磷酸盐钠盐可用于DNA合成反应，如PCR、DNA测序和分子克隆技术。
2′-Deoxyadenosine 5′-triphosphate sodium salt solution has been used as a component of the dNTP mix for labelling of ribosomal 18s rDNA probe and telomeric (TTAGG)n probe.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

分析證明 (COA)

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Spittlebugs (Hemiptera)
Kuznetsova V G, et al.
Protocols for Cytogenetic Mapping of Arthropod Genomes., 351-380 (2015)
Kousuke Sato et al.
Chembiochem : a European journal of chemical biology, 12(15), 2341-2346 (2011-09-03)
We herein describe the synthesis of fluorescent 5-(5,6-dimethoxybenzothiazol-2-yl)-2'-deoxyuridine 5'-triphosphate (d(bt)UTP) and primer extension reactions using d(bt)UTP. We also carried out primer extension reactions using the (bt)U template. B family DNA polymerases, such as KOD, Deep Vent (exo-), and 9°N(m) DNA
Christina M Zimanyi et al.
Structure (London, England : 1993), 20(8), 1374-1383 (2012-06-26)
Ribonucleotide reductases (RNRs) provide the precursors for DNA biosynthesis and repair and are successful targets for anticancer drugs such as clofarabine and gemcitabine. Recently, we reported that dATP inhibits E. coli class Ia RNR by driving formation of RNR subunits
Paul J Rothwell et al.
The Journal of biological chemistry, 288(19), 13575-13591 (2013-03-26)
Conformational selection plays a key role in the polymerase cycle. Klentaq1 exists in conformational equilibrium between three states (open, closed, and “nucleotide-binding”) whose level of occupancy is determined by the bound substrate. The “nucleotide-binding” state plays a pivotal role in
U C Halder et al.
Cell death & disease, 2, e197-e197 (2011-09-02)
During early infection, viruses activate cellular stress-response proteins such as heat-shock proteins (Hsps) to counteract apoptosis, but later on, they modulate these proteins to stimulate apoptosis for efficient viral dissemination. Hsp70 has been attributed to modulate viral entry, transcription, nuclear
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