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Key Documents

D4000

Sigma-Aldrich

反式-脱氢雄甾酮

≥99%

同義詞:

3β-羟基-5-雄烯-17-酮, DHEA, 去氢表雄酮, 普拉睾酮, 脱氢异雄酮, 雄素-5-烯-3β-醇-17-酮

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About This Item

經驗公式(希爾表示法):
C19H28O2
CAS號碼:
分子量::
288.42
Beilstein:
2058110
EC號碼:
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:
NACRES:
NA.77

生物源

synthetic (organic)

品質等級

化驗

≥99%

形狀

crystalline powder

drug control

Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

mp

149-151 °C (lit.)

溶解度

chloroform: 50 mg/mL, clear, colorless

運輸包裝

ambient

儲存溫度

room temp

SMILES 字串

C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1

InChI 密鑰

FMGSKLZLMKYGDP-USOAJAOKSA-N

尋找類似的產品? 前往 產品比較指南

生化/生理作用

GABAA 受体的负调节剂。肾上腺分泌的类固醇,具有雌激素和雄激素特性。 它转化为 5-雄烯二醇(一种有效的雌激素)可增强雌激素敏感性乳腺肿瘤的生长和存活率。在高浓度但生理有效的条件下,DHEA 抑制嗜铬细胞祖细胞的增殖并诱导多巴胺能分化。
脱氢雄激素(DHEA)是 GABAA 受体的负调节剂。它是肾上腺分泌的类固醇,具有雌激素和雄激素特性。 脱氢表雄酮(DHEA)转化为 5-雄烯二醇(一种有效的雌激素)可增强雌激素敏感性乳腺肿瘤的生长和存活率。

象形圖

Health hazard

訊號詞

Warning

危險聲明

危險分類

Repr. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Nikolaos E Koundourakis et al.
Hormones (Athens, Greece), 18(2), 151-172 (2019-07-01)
A constant topic reported in the lay press is the effect of sex hormones on athletic performance and their abuse by athletes in their effort to enhance their performance or to either boost or sidestep their hard, protracted, and demanding
Sarah Whittle et al.
Social cognitive and affective neuroscience, 10(9), 1282-1290 (2015-02-14)
Early timing of adrenarche, associated with relatively high levels of Dehydroepiandrosterone (DHEA) in children, has been associated with mental health and behavioral problems. However, little is known about effects of adreneracheal timing on brain function. The aim of this study
D J Handelsman et al.
Human reproduction (Oxford, England), 32(2), 418-422 (2016-12-22)
How well does multi-analyte steroid mass spectrometry (MS) profiling classify women with and without polycystic ovary syndrome (PCOS)? Our liquid chromatography MS (LC-MS) steroid profiling only minimally improves discrimination of women with and without PCOS compared with a direct testosterone
Thomas Piper et al.
Drug testing and analysis, 9(11-12), 1695-1703 (2017-08-25)
In the course of investigations into the metabolism of testosterone (T) by means of deuterated T and hydrogen isotope ratio mass spectrometry, a pronounced influence of the oral administration of T on sulfoconjugated steroid metabolites was observed. Especially in case
Y Zimmerman et al.
Contraception, 91(2), 134-142 (2014-12-17)
Combined oral contraceptives (COCs) decrease androgen levels, including testosterone (T), which may be associated with sexual dysfunction and mood complaints in some women. We have shown that 'co-administration' of dehydroepiandrosterone (DHEA) to a drospirenone (DRSP)-containing COC restored total T levels

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