推薦產品
生物源
synthetic (organic)
化驗
≥98%
形狀
powder
mp
259-262 °C (lit.)
溶解度
water: 50 mg/mL, clear to hazy, colorless to light yellow
儲存溫度
−20°C
SMILES 字串
CN(C)c1ncnc2[nH]cnc12
InChI
1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)
InChI 密鑰
BVIAOQMSVZHOJM-UHFFFAOYSA-N
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一般說明
6-二甲氨基嘌呤(6-DMAP)是一种嘌呤类代谢物,含有2个缩合杂环及与腺嘌呤的嘌呤氨基(环外氨基)连接的2个甲基。
應用
6-二甲氨基嘌呤已用于:
- 作为GR-1 aa培养基(牛培养基)补充剂,用于牛卵母细胞的孤雌激活,以研究其对胚胎发育的影响
- 核移植胚胎生产中的激活步骤
- 作为HCR2aa培养基补充剂,用于激活通过异种体细胞核移植(iSCNT)技术获得的异种胚胎
生化/生理作用
6-二甲氨基嘌呤(6-DMAP)是一种蛋白激酶和细胞周期蛋白依赖性激酶抑制剂。它是一种次生代谢产物,介导RNA修饰。6-DMAP是一种强效的细胞质分裂抑制剂,用于孤雌生殖和减数分裂研究。它也可用于促进哺乳动物卵母细胞的前核形成。根据飞秒荧光上转换光谱技术,6-DMAP是一种双荧光(dual fluorescence)分子。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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