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Merck
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重要文件

D2396

Sigma-Aldrich

Dimenhydrinate

同義詞:

N-(2-Diphenylmethoxyethyl)-N,N-dimethylammonium 8-chlorotheophyllinate

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About This Item

經驗公式(希爾表示法):
C17H21NO · C7H7ClN4O2
CAS號碼:
分子量::
469.96
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.77

形狀

powder

品質等級

SMILES 字串

CN1C(=O)N(C)c2nc(Cl)[nH]c2C1=O.CN(C)CCOC(c3ccccc3)c4ccccc4

InChI

1S/C17H21NO.C7H7ClN4O2/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h3-12,17H,13-14H2,1-2H3;1-2H3,(H,9,10)

InChI 密鑰

NFLLKCVHYJRNRH-UHFFFAOYSA-N

基因資訊

human ... HRH1(3269)

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一般說明

Dimenhydrinate is a salt of antihistamine drugs, such as diphenhydramine and 8-chlorotheophylline. It has antiemetic properties. Dimenhydrinate is used to treat nausea and vomiting during pregnancy.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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Serge Gouin et al.
Pediatrics, 129(6), 1050-1055 (2012-05-16)
To evaluate the efficacy and safety of oral dimenhydrinate in the treatment of acute gastroenteritis. This was a randomized, double-blind, placebo-controlled trial conducted in the emergency department of a pediatric university-affiliated center. Children 1 to 12 years old who presented
Gerard Nobel et al.
Brain research bulletin, 82(3-4), 193-200 (2010-04-17)
Motion sickness (MS) exaggerates body cooling during cold-water immersion. The aim of the present study was to investigate whether such MS-induced predisposition to hypothermia is influenced by two anti-MS drugs: the histamine-receptor blocker dimenhydrinate (DMH) and the muscarine-receptor blocker scopolamine
Faisal Karmali et al.
Journal of vestibular research : equilibrium & orientation, 20(1), 31-43 (2010-06-18)
Commercial sub-orbital operators will soon offer the excitement of traveling to space to thousands of people. Based on previous experience in space flight and parabolic flight, sensorimotor disruptions in eye movements, postural stability, and motor coordination are likely in these
Ulrike Uhlig et al.
Pediatrics, 124(4), e622-e632 (2009-09-16)
Vomiting is a common symptom in children with infectious gastroenteritis. It contributes to fluid loss and is a limiting factor for oral rehydration therapy. Dimenhydrinate has traditionally been used for children with gastroenteritis in countries such as Canada and Germany.
Matthias Voigt et al.
Journal of clinical anesthesia, 23(6), 461-468 (2011-09-14)
To evaluate strategies to treat postoperative nausea and vomiting (PONV) in patients undergoing elective breast surgery. Prospective, randomized, double-blinded, placebo-controlled trial. University-affiliated hospital. 480 patients with risk factors for PONV. Patients were randomized to three groups to receive an antiemetic

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