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Key Documents

D0754

Sigma-Aldrich

3,5-二碘- L -酪氨酸 二水合物

≥98.0% (HPLC), suitable for ligand binding assays

同義詞:

3,5-diiodo-L-tyrosine hydrate (1:2)

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About This Item

經驗公式(希爾表示法):
C9H9I2NO3 · 2H2O
CAS號碼:
分子量::
469.01
Beilstein:
2218691
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26

product name

3,5-二碘- L -酪氨酸 二水合物, crystalline

化驗

≥98.0% (HPLC)

形狀

crystalline

技術

ligand binding assay: suitable

顏色

white

mp

200 °C (dec.) (lit.)

溶解度

4 M NH4OH in methanol: 50 mg/mL, clear, yellow-green

儲存溫度

−20°C

SMILES 字串

N[C@@H](Cc1cc(I)c(O)c(I)c1)C(O)=O

InChI

1S/C9H9I2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1

InChI 密鑰

NYPYHUZRZVSYKL-ZETCQYMHSA-N

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應用

用于测定卤化酪氨酸和甲状腺激素转氨酶的底物。 甲状腺激素生物合成和替代代谢途径中的中间体。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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A Balsam et al.
The Journal of clinical investigation, 72(4), 1234-1245 (1983-10-01)
Studies were performed to elucidate the nature of the pathway of hepatic thyroxine (T4) metabolism that is activated by inhibitors of liver catalase. For this purpose, the metabolism of T4 in homogenates of rat liver was monitored with T4 labeled
Jana Frýdlová et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 863(1), 135-140 (2008-02-08)
The interaction of porcine pepsin A with immobilized derivatives of aromatic amino acids was investigated. Divinyl sulfone-activated Sepharose was used to immobilize N-acetyl-l-phenylalanine and 3,5-diiodo-l-tyrosine via their free carboxyl groups and l-tyrosine via its amino group. Immobilized l-tyrosine was iodinated
Sangeeta Kumari et al.
Journal of the American Society for Mass Spectrometry, 18(8), 1516-1524 (2007-06-26)
L-Tyrosine and iodinated L-tyrosines, i.e., 3-iodo-L-tyrosine and 3,5-diiodo-L-tyrosine, are successfully used as chiral references for the chiral discrimination of aliphatic, acidic, and aromatic amino acids. Chiral discrimination is achieved by investigating the collision-induced dissociation spectra of the trimeric complex [Cu(II)(ref)(2)(A)
Yining Zheng et al.
Talanta, 69(1), 107-112 (2008-10-31)
In this paper, a new method for separation, identification and quantitation of iodotyrosines and iodothyronines [3-monoiodo-L-tyrosine (MIT), 3,5-diiodo-L-tyrosine (DIT), L-thyronine (T(0)), 3,5-diiodo-L-thyronine (T(2)), 3,5,3'-triiodo-L-thyronine (T(3)) and 3,3',5,5'-tetraiodo-L-thyronine (T(4))] was described by using capillary electrophoresis with photodiode-array ultraviolet-visible detection (CE-UV). The
M. Nakano
Methods in Enzymology, 17A, 660-660 (1970)

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