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Merck
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Key Documents

D0633

Sigma-Aldrich

7-(2,3-二羟丙基)茶碱

同義詞:

喘定

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About This Item

經驗公式(希爾表示法):
C10H14N4O4
CAS號碼:
分子量::
254.24
Beilstein:
284563
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.77

形狀

powder

mp

161-162 °C (lit.)

SMILES 字串

CN1C(=O)N(C)c2ncn(CC(O)CO)c2C1=O

InChI

1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3

InChI 密鑰

KSCFJBIXMNOVSH-UHFFFAOYSA-N

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生化/生理作用

7-(2,3-Dihydroxypropyl)theophylline is also called as dyphylline. Dyphylline serves as a bronchodilator and aids in better air flow through the lungs. It reduces the symptoms of chronic lung disorder such as asthma and bronchitis.

特點和優勢

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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F Siepmann et al.
Journal of controlled release : official journal of the Controlled Release Society, 141(2), 216-222 (2009-09-10)
Kollidon SR-based matrix tablets containing various amounts of diprophylline were prepared and thoroughly characterized in vitro. This includes drug release measurements in 0.1M HCl and phosphate buffer pH 7.4, monitoring of changes in the tablet's height and diameter, morphology as
Sinan Güres et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 80(1), 122-129 (2011-10-20)
The aim of this study was to use a mechanistically realistic mathematical model based on Fick's second law to quantitatively predict the release profiles from solid lipid extrudates consisting of a ternary matrix. Diprophylline was studied as a freely water-soluble
Wei-Shan Huang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 795(2), 329-335 (2003-10-03)
A simple micellar electrokinetic chromatography is described for well resolution of theophylline, dyphylline and caffeine. The separation was performed at 25 degrees C using a background electrolyte consisting of 10mM borate buffer at pH 9 and 40 mM sodium dodecyl
Mario Grassi et al.
International journal of pharmaceutics, 276(1-2), 107-114 (2004-04-29)
A mathematical model able to describe the release kinetics of two model drugs (Diprophylline and Theophylline) from partially coated hydroxypropylmethylcellulose (HPMC, Methocel) K4M) matrices is presented. As solvent interaction with the system and drug release can only take place in
The AARP Guide to Pills: Essential Information on More Than 1,200 Prescription and Nonprescription Medicines, Including Generics, 302-302 (2006)

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