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C9749

Sigma-Aldrich

CBiPES hydrochloride

≥98% (HPLC)

同義詞:

N-(4′-cyano[1,1′-biphenyl]-3-yl)-N-(3-pyridinylmethyl)-ethanesulfonamide hydrochloride

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About This Item

經驗公式(希爾表示法):
C21H19N3O2S · HCl
CAS號碼:
分子量::
413.92
分類程式碼代碼:
12352200
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated

顏色

off-white to light brown

溶解度

DMSO: >20 mg/mL

起源

Eli Lilly

儲存溫度

2-8°C

InChI

1S/C21H19N3O2S.ClH/c1-2-27(25,26)24(16-18-5-4-12-23-15-18)21-7-3-6-20(13-21)19-10-8-17(14-22)9-11-19;/h3-13,15H,2,16H2,1H3;1H

InChI 密鑰

QKUHSVQWWZBAKM-UHFFFAOYSA-N

生化/生理作用

CBiPES is a positive allosteric modulator of the mGlu2 receptor. CBiPES attenuates stress-induced hyperthermia and blocks the hyperlocomotor effects of PCP in murine models. In rat brain, CBiPES attenuates ketamine-induced increase in extracellular histamine concentration. This compound is a sulfonamide, different chemical class from other mGlu2R agonists in the Sigma catalog.

特點和優勢

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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文章

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