C6348

Monoclonal Anti-CXCR2 (IL-8 RB) antibody produced in mouse

clone 48311.211, purified immunoglobulin, lyophilized powder

• MDL號碼: MFCD01864633
• 分類程式碼代碼: 51111800
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 48311.211, monoclonal
• 形狀: lyophilized powder
• 物種活性: human
• 技術: flow cytometry: suitable; neutralization: suitable
• 同型: IgG2a
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... IL8RB(3579) ; mouse ... Il8rb(12765)

描述

一般說明

The antibody will neutralize human cell surface CXCR-2 mediated-myloperoxidase release from human granulocytes induced by GROα. It will not block myeloperoxidase release induced by IL-8. The antibody reacts with human CXCR-2 transfectant cells and not the parent cell line. The antibody shows no cross-reactivity with CXCR-1.

免疫原

human CXCR2 transfected NSO mouse myeloma cells.

生化／生理作用

CXCR2 is a G protein-coupled receptor that binds IL-8 with high affinity. It mediates migration of neutrophils to the sites of inflammation. It also binds CXCL1 and stimulates growth of melanomas.

外觀

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

準備報告

Purified using protein G.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)