跳轉至內容
Merck
全部照片(1)

重要文件

C6116

Sigma-Aldrich

(+/-)-氯前列醇钠盐水合物 钠盐 水合物

≥98% (HPLC), powder

同義詞:

7-[2-[4-(3-氯苯氧基)-3-羟基丁-1-烯基]-3,5-二羟基环戊基]庚-5-烯酸钠 钠盐 水合物

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C22H28ClNaO6 · xH2O
CAS號碼:
分子量::
446.90 (anhydrous basis)
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated

顏色

light brown

mp

68-70 °C

溶解度

H2O: >10 mg/mL

儲存溫度

−20°C

SMILES 字串

[Na+].[H]O[H].O[C@@H](COc1cccc(Cl)c1)\C=C\[C@H]2[C@H](O)C[C@H](O)[C@@H]2C\C=C/CCCC([O-])=O

InChI

1S/C22H29ClO6.Na.H2O/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28;;/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28);;1H2/q;+1;/p-1/b3-1-,11-10+;;/t16-,18-,19-,20+,21-;;/m1../s1

InChI 密鑰

ZEQHRVULQBYULU-LPFHDDPUSA-M

尋找類似的產品? 前往 產品比較指南

一般說明

氯前列醇是前列腺素F2α(PGF)的合成类似物。 氯前列醇有助于诱导动物发情,并具有子宫收缩作用。氯前列醇会诱发动物流产。

應用

(+/-)-氯前列醇钠盐水合物已用于研究其对小鼠发情同期和子宫发育的影响。

生化/生理作用

氯前列醇是一种有效的FP前列腺素类受体激动剂。
氯前列醇是一种有效的FP前列腺素类受体激动剂。与氟前列醇相比,氯前列醇更有效,但选择性较低。对于EP和TP前列腺素受体,氯前列醇与PGF 的效力相近。它可用于治疗母猪和小母猪的不孕症。

特點和優勢

《受体分类和信号转导》手册的 前列腺素类受体 页面有该化合物的介绍。想要浏览手册的其他页面, 请单击此处

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Muhammad Modu Bukar et al.
Reproductive biology, 12(3), 325-328 (2012-11-17)
The effects of estrus synchronization with prostaglandin F(2α) (PGF(2α)) and Controlled Internal Drug Release Device (CIDR) on ensuing antral follicular development were documented and compared to natural estrous cycles of non-seasonal tropical goats. Two to six follicular waves were observed
M C García Mitacek et al.
Reproduction in domestic animals = Zuchthygiene, 47 Suppl 6, 200-203 (2013-01-04)
The objective of this study was to evaluate the efficacy of cloprostenol (CLO) or aglepristone (ALI) for pregnancy termination in queens at 21-22 and 35-38 days of gestation. Two experiments (EXP) were carried out to accomplish this aim. Thirty-seven 12-
Iwona Dams et al.
Chirality, 25(3), 170-179 (2013-02-06)
The 17-phenyl PGF(2α) analogue bimatoprost (10a) is the most efficacious ocular hypotensive agent currently available for the treatment of glaucoma or ocular hypertension. A novel convergent synthesis of 13,14-en-15-ol prostamideF(2α) analogues was developed employing Julia-Lythgoe olefination of the structurally advanced
A study of two protocols combining aglepristone and cloprostenol to treat open cervix pyometra in the bitch
Gobello Cristina, et al.
Theriogenology, 60(5), 901-908 (2003)
Mano Sira et al.
Aesthetic surgery journal, 32(7), 822-824 (2012-09-04)
The prostaglandin F2a (PGF2a) analogue bimatoprost 0.03% (Allergan, Inc, Irvine, California) has been employed for the treatment of hypotrichosis since it gained Food and Drug Administration approval as Latisse in 2008. In this report, the authors retrospectively review the cases

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務