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Merck
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文件

C6013

Sigma-Aldrich

胆甾醇半琥珀酸酯 三羟甲基氨基甲烷盐

anionic detergent

同義詞:

3β-Hydroxy-5-cholestene 3-hemisuccinate, CHEMS, CHS, 胆固醇半琥珀酸酯, 胆甾醇琥珀酸酯

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About This Item

經驗公式（希爾表示法）:
C31H50O4 · C4H11NO3
CAS號碼:
102601-49-0
分子量：:
607.86
MDL號碼:
MFCD00058298
分類程式碼代碼:
12352211
eCl@ss:
39023139
PubChem物質ID:
329775108
NACRES:
NA.77

生物源

synthetic (organic)

化驗

≥98% (TLC)

形狀

powder

官能基

ester

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

NC(CO)(CO)CO.CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)CCC(O)=O

InChI

1S/C31H50O4.C4H11NO3/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5;5-4(1-6,2-7)3-8/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33);6-8H,1-3,5H2/t21-,23+,24+,25-,26+,27+,30+,31-;/m1./s1

InChI 密鑰

SLDYONDUXRBLLR-XTCKSVDZSA-N

相關類別

應用

胆固醇半琥珀酸酯三盐用于：
  • 制备用于葡聚糖合酶测定的溶解缓冲液
  • 制备用于将阿片受体固定在顺磁珠上的免疫沉淀缓冲液。
  • 作为脂质体和蛋白突触结合蛋白1的膜稳定剂
  • 作为叶酸修饰的自微乳化药物递送系统的组成部分。
  • 与正十二烷基 β-D-麦芽糖苷（DDM）一起用于溶解红细胞血影和趋化因子受体CCR1
  • 用于溶解蛋白

生化／生理作用

胆固醇半琥珀酸盐是一种可电离的阴离子洗涤剂，可稳定大的单层囊泡。这些脂质体囊泡作为抗癌药物、寡核苷酸和抗生素的递送剂。据报道胆固醇琥珀酸酯还具有抗增殖活性，并可以在临床上用作抗肿瘤剂。

準備報告

浓度为1 mg/ml的半琥珀酸胆固醇三盐在甲醇中生成澄清、无色的溶液。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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