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Merck
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重要文件

AV44083

Sigma-Aldrich

Anti-SLC5A11 antibody produced in rabbit

affinity isolated antibody

同義詞:

Anti-KST1, Anti-RKST1, Anti-SGLT6, Anti-SMIT2, Anti-Solute carrier family 5 (sodium/glucose cotransporter), member 11

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

74 kDa

物種活性

horse, mouse, goat, human, guinea pig, rat, bovine, rabbit, dog

濃度

0.5 mg - 1 mg/mL

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

免疫原

Synthetic peptide directed towards the middle region of human SLC5A11

應用

Anti-SLC5A11 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.

生化/生理作用

SLC5A11 is a sodium/glucose cotransporter that uses ion gradients to drive active transport of nutrients, neurotransmitters, osmolytes and ions. It interacts with TNF-α, programmed cell death 1 (PDCD1) and complement component 4 (C4) and may induce apoptosis via the TNF-α - PDCD1 pathway. The gene encoding for this transporter also acts as an autoimmune modifier gene.

序列

Synthetic peptide located within the following region: VGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPWPGVL

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

L-J Tsai et al.
Tissue antigens, 71(2), 114-126 (2007-12-12)
Genetic studies in several human autoimmune diseases suggest that the pericentromeric region of chromosome 16 might harbor an autoimmune modifier gene. We hypothesized that the sodium-dependent glucose cotransporter gene SLC5A11 is such a gene, and so might interact with immune-related

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