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Merck
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Key Documents

AV34401

Sigma-Aldrich

Anti-IER2 antibody produced in rabbit

affinity isolated antibody

同義詞:

Anti-ETR101, Anti-Immediate early response 2, Anti-MGC111472, Anti-MGC15265

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

24 kDa

物種活性

human

濃度

0.5 mg - 1 mg/mL

技術

immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... IER2(9592)

相關類別

一般說明

IER2 is an immediate early response gene that regulates FGF signaling and patterning in zebrafish. It is also known to enhance tumor cell invasion, and hence functions as a prognostic marker for colorectal cancer.
Rabbit Anti-IER2 antibody recognizes human IER2.

免疫原

Synthetic peptide directed towards the N terminal region of human IER2

應用

Rabbit Anti-IER2 antibody can be used for western blot applications at a concentration of 1 μg/ml. It can also be used for IHC applications at 4-8 μg/ml, using paraffin-embedded tissues.

序列

Synthetic peptide located within the following region: LYLSAKVEALEPEVSLPAALPSDPRLHPPREAESTAETATPDGEHPFPEP

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Sung-Kook Hong et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(7), 2230-2235 (2009-01-24)
Establishment of left-right asymmetry in vertebrates requires nodal, Wnt-PCP and FGF signaling and involves ciliogenesis in a laterality organ. Effector genes through which FGF signaling affects laterality have not been described. We isolated the zebrafish ier2 and fibp1 genes as
A Neeb et al.
Oncogene, 31(33), 3796-3806 (2011-11-29)
Here, we report unbiased screens for genes expressed in metastatic tumor cells that are associated with cell motility. These screens identified Ier2, an immediate early gene of unknown function, as potentially having a role in tumor cell motility and metastasis.

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