AV32623

Anti-HIC1 antibody produced in rabbit

affinity isolated antibody

• 同義詞: Anti-Hypermethylated in cancer 1
• 分類程式碼代碼: 12352203
• NACRES: NA.43
• 無性繁殖: polyclonal
• application: WB
• 物種活性: human
• 技術: western blot: suitable
• citations: 1

屬性

• 生物源: rabbit
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 74 kDa
• 物種活性: human
• 濃度: 0.5 mg - 1 mg/mL
• 技術: western blot: suitable
• NCBI登錄號: NP_001091672
• UniProt登錄號: Q14526-2
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... HIC1(3090)

描述

一般說明

HIC1 is a tumor suppressor that interacts with SIRT1 to regulate p53-depenedent responses to DNA damage.
Rabbit Anti-HIC1 antibody recognizes human, mouse, and rat HIC1.

免疫原

Synthetic peptide directed towards the N terminal region of human HIC1

應用

Rabbit Anti-HIC1 antibody can be used for western blot applications at a concentration of 0.25μg/ml.

生化／生理作用

HIon Channel1 is a transcriptional repressor. HIon Channel1 may act as a tumor suppressor. HIon Channel1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIon Channel1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.

序列

Synthetic peptide located within the following region: ALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELPPRPDSPPSAGPA

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable