AC-0362

ACTH (EP390) Rabbit Monoclonal Primary Antibody

• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 抗體表格: Ig fraction of antiserum
• 無性繁殖: monoclonal
• 描述: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 形狀: buffered aqueous solution
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
• 同型: IgG
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 視覺化: cytoplasmic

描述

一般說明

Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced from corticotropes in the anterior lobe of the pituitary gland. ACTH is released by corticotropin-releasing hormone stimulation by the hypothalamus in response to biological stress. Identifying ACTH is useful in the classification of pituitary tumors and diseases. Cushing′s disease derived from ACTH producing adenomas represents 10-15% of pituitary tumors. By immunohistochemistry (IHC), these tumors are immunoreactive for ACTH, beta-Lipotropin, and beta-endorphin. ACTH is also detected in a subset of growth hormone (GH), thyroid-stimulating hormone (TSH) and follicle-stimulating hormone (FSH) secreting adenomas. With the exception for ACTH secreting adenomas, most functioning adenomas are usually macroadenomas; tumors larger than 10 mm. A combination of ACTH IHC and reticulin staining also provides utility in the differential diagnosis between pituitary adenoma versus corticotroph hyperplasia. Breakdown of acinar structure and ACTH immunoreactivity are suggestive of adenoma.

品質

IVD

IVD

IVD

RUO

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and &lt0.1% Sodium Azide

其他說明

For a copy of the IFU and CofA contact IVDorder@ABCAM.com

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable