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Merck
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重要文件

A8786

Sigma-Aldrich

抗 小鼠 IgM(μ-链特异性)– 过氧化物酶 山羊抗

affinity isolated antibody, buffered aqueous solution

同義詞:

Goat Anti-Mouse IgM (μ-chain specific)–HRP

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

goat

共軛

peroxidase conjugate

抗體表格

affinity isolated antibody

抗體產品種類

secondary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

技術

direct ELISA: 1:10,000

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

一般說明

IgM 是一种调节体液免疫反应的糖蛋白抗体。小鼠 IgM 参与调节 B 细胞记忆。该抗体同种型还涉及与小鼠 1 型糖尿病发病机理相关的自身免疫反应的发展。针对纯化的小鼠IgA、IgM和IgG进行测试时,抗小鼠IgG(μ-链特异性)-过氧化物酶抗体对小鼠IgM具有特异性。

免疫原

纯化小鼠 IgM

應用

抗小鼠 IgM (μ-链特异性)-过氧化物酶抗体还可用于:
  • 蛋白质印迹
  • 酶联免疫吸附测定(ELISA)
  • 免疫组化

外觀

0.01 M磷酸盐缓冲液(pH 7.4,含有带保存剂的1%牛血清白蛋白)溶液。

準備報告

采用 Wilson,M.B. 和 Nakane,P.K. 在《免疫荧光及相关染色技术》(Immunofluorescence and Related Staining Techniques) 中描述的过碘酸盐法制备(Elsevier/North Holland Biomedical Press 出版社,Amsterdam,p215 (1978))。

免責聲明

除非我们的产品目录或产品随附的其他公司文件中另有说明,否则我们的产品仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途或任何类型的人类或动物消费或应用。

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象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Aquatic Chronic 3 - Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Fernando Goñi et al.
PloS one, 5(10), e13391-e13391 (2010-10-23)
Many neurodegenerative diseases are characterized by the conformational change of normal self-proteins into amyloidogenic, pathological conformers, which share structural properties such as high β-sheet content and resistance to degradation. The most common is Alzheimer's disease (AD) where the normal soluble
M A Bründler et al.
European journal of immunology, 26(9), 2257-2262 (1996-09-01)
Mice rendered B cell deficient by targeted disruption of the immunoglobulin mu chain gene (IgM-/- mice) were used to analyze the role of antibodies and B cells in viral infections; homozygous IgM-/- mice were bred in a way to avoid
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Journal of immunology (Baltimore, Md. : 1950), 172(6), 3913-3921 (2004-03-09)
Lupus nephritis is characterized by immune complex deposition and infiltration of inflammatory cells into the kidney including Ab-producing cells (AbPCs). Although AbPCs play a central role in the pathogenesis of immune complex glomerulonephritis in lupus, the specificity and pathogenic role
Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity
Bindesboll C, et al.
Journal of Lipid Research, 56(4) (2015)
Fernando Goñi et al.
Journal of neuroinflammation, 10, 150-150 (2013-12-18)
Central to the pathogenesis of Alzheimer's disease (AD) and many other neurodegenerative diseases is the conformational change of a normal self-protein into toxic oligomeric species and amyloid deposits. None of these disorders have an effective therapy, but immunization approaches hold

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