A6531

Anti-Mouse IgG (whole molecule)−Agarose antibody produced in goat

affinity isolated antibody, suspension

• MDL號碼: MFCD03791275
• 分類程式碼代碼: 12352203
• NACRES: NA.46

屬性

• 生物源: goat
• 品質等級: 200
• 共軛: agarose conjugate
• 抗體表格: affinity isolated antibody
• 抗體產品種類: secondary antibodies
• 無性繁殖: polyclonal
• 形狀: suspension
• 物種活性: mouse
• 標籤範圍: ≥5 mg per mL
• 技術: Ouchterlony double diffusion: suitable; immunoprecipitation (IP): suitable
• 基質: Cross-linked 4% beaded agarose
• 基質活化: cyanogen bromide
• 基質墊片: 1 atom
• 容量: 0.4 mg/mL, resin binding capacity (mouse IgG)
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified

描述

一般說明

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mice consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE.

Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases. Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice. Goat Anti-Mouse IgG (whole molecule)-Agarose antibodies bind to all mouse IgG subclasses.

免疫原

IgG isolated from pooled normal mouse serum

應用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper)
Immunoprecipitation (1 paper)

Goat Anti-Mouse IgG (whole molecule)-Agarose antibodies have been used for immunoprecipiation assays. The product can also be used for Ouchterlony double diffusion applications.

Soluble antigens from meningococci extracts were mixed with ascitic fluid containing primary antibody and 50 μl of agarose-linked goat anti-mouse IgG for 5 hours at 4 °C.

生化／生理作用

IgG helps in opsonization, complement fixation and antibody-dependent cell-mediated cytotoxicity. Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. IgG2a of IgG has cytotropic properties and IgG2 molecules have the ability to activate complement.

外觀

Suspension in 0.5 M NaCl containing preservative

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3