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Key Documents

A3606

Sigma-Aldrich

Anti-ATG3 (C-terminal) 兔抗

IgG fraction of antiserum, buffered aqueous solution

同義詞:

Anti-APG3, Anti-APG3L, Anti-Autophagy related 3 homolog (S. cerevisiae), Anti-DKFZp564M1178, Anti-FLJ22125, Anti-MGC15201, Anti-PC3-96

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

IgG fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~36 kDa

物種活性

rat, human, mouse

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 using biotin/ExtrAvidin®-peroxidase staining of heat-retrieved sections of human cerebellum
immunoprecipitation (IP): 2-4 μL using rat NRK and mouse 3T3 cell lysates

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... ATG3(64422)
mouse ... Atg3(67841)

一般說明

Rabbit Anti-ATG3 (C-terminal) antibody recognizes human, rat, and mouse Atg3 by immunoprecipitation (approx. 36kDa) and immunohistochemistry. Detection of the Atg3 staining by immunohistochemistry is specifically inhibited with the immunizing peptide.

免疫原

synthetic peptide corresponding to amino acids 298-314 of human ATG3, conjugated to KLH via an N-terminal cysteine residue.

應用

Rabbit Anti-ATG3 (C-terminal) antibody can be used for immunohistochemistry (1:50 -1:100) and immunoprecipitation (2-4μl) assays.

標靶描述

ATG3 is a member of the autophagy-related protein family and is involved in the formation of the autophagosome.

外觀

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

法律資訊

ExtrAvidin is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

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Qing-Hua Cao et al.
American journal of translational research, 8(9), 3831-3847 (2016-10-12)
Autophagy-related (ATG) genes contributed to tumorigenesis and cancer progression. This study aims to investigate the expression of ATG proteins and their clinicopathological significance in gastric cancer. Nine well-known ATG proteins, (ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12 and
Zhiyuan You et al.
Autophagy, 15(8), 1309-1321 (2019-02-16)
TP53INP2/DOR (tumor protein p53-inducible nuclear protein 2) contributes to mammalian macroautophagy/autophagy by carrying nuclear deacetylated MAP1LC3/LC3 to the cytoplasm. Here, we report that in the cytoplasm, TP53INP2 further functions in autophagosome biogenesis by promoting LC3B-ATG7 interaction. Cytoplasmic expression of the

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