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Key Documents

A3010

Sigma-Aldrich

酰基酶Ⅰ 来源于猪肾脏

Grade I, lyophilized powder, ≥1500 units/mg protein

同義詞:

N-酰基氨基酸酰胺水解酶, 氨基酰化酶

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About This Item

CAS號碼:
酶委員會編號:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

種類

Grade I

品質等級

形狀

lyophilized powder

比活性

≥1500 units/mg protein

成份

Protein, ≥60%

UniProt登錄號

儲存溫度

−20°C

基因資訊

尋找類似的產品? 前往 產品比較指南

應用

猪肾中的酰化酶 I 已被用于研究各种 S-烷基-N-乙酰基-L-半胱氨酸及其碳、氧类似物的酰化酶 I 催化的脱乙酰作用 。酰化酶 I 可能有助于催化 N-乙酰氨基酸生成对映体纯的 L-氨基酸

生化/生理作用

酰化酶 I 催化 N-乙酰基-L-半胱氨酸和 S-烷基-N-乙酰基-L-半胱氨酸的脱乙酰化。正丁基丙二酸是酰化酶 Ⅰ 的抑制剂。S-烷基-N-乙酰基-L-半胱氨酸与短 (C0-C3) 和不分枝 S-烷基取代已被发现是良好的酰化酶 I 底物。

單位定義

一个单元将在pH 7.0 和 25°C 条件下每小时水解 1.0μmol N-乙酰- L -蛋氨酸。

分析報告

缩二脲法测定蛋白

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Y Fukagawa et al.
The Journal of antibiotics, 33(6), 543-549 (1980-06-01)
PS-5 was deacetylated to NS-5 (deacetylated PS-5) by l-amino acid acylase from porcine kidney and D-amino acid acylase from Streptomyces olivaceus but not by l-amino acid acylase from Aspergillus sp. Using PS-5, N-chloroacetyl-l-phenylalanine and N-chloroacetyl-D-valine as substrates, acylase producers were
A S Bommarius et al.
Annals of the New York Academy of Sciences, 672, 126-136 (1992-11-30)
The method of measuring enzyme deactivation by monitoring necessary addition of fresh enzyme to keep a constant degree of conversion in a CSTR at constant [E] x tau, the product of concentration of active enzyme [E] and residence time tau
V Uttamsingh et al.
Chemical research in toxicology, 11(7), 800-809 (1998-07-22)
The aminoacylase that catalyzes the hydrolysis of N-acetyl-L-cysteine (NAC) was identified as acylase I after purification by column chromatography and electrophoretic analysis. Rat kidney cytosol was fractionated by ammonium sulfate precipitation, and the proteins were separated by ion-exchange column chromatography
Xiaoyong Liu et al.
Journal of invertebrate pathology, 105(1), 84-90 (2010-05-18)
Silkworm hemolymph is an important defense tissue to resist bacteria and virus infections. To study the response of silkworm hemolymph in the resistance of Bombyx mori L. nucleopolyhedrovirus (BmNPV), we constructed a near-isogenic silkworm line with BmNPV resistance using highly
Albert P Chen et al.
NMR in biomedicine, 24(5), 514-520 (2011-06-16)
Reporter-based cell detection and localization in vivo may become an important imaging tool with the emergence of cellular therapy. With the strong signal enhancement provided by dynamic nuclear polarization, an NMR-based reporter probe system utilizing specific enzyme expression and activity

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