推薦產品
生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
IgG fraction of antiserum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
分子量
antigen ~50 kDa
物種活性
human
包裝
vial of 2 mL lyophilized antiserum
技術
immunoelectrophoresis: suitable
indirect ELISA: 1:30,000-1:60,000
UniProt登錄號
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
human ... SERPINA1(5265)
一般說明
α-1-抗胰蛋白酶属于丝酶抑制蛋白家族，是一种活性很强的丝氨酸蛋白酶抑制剂。其关键作用是保护下呼吸道免受人白细胞弹性蛋白酶的水解破坏。AAT基因突变会降低血清中α-1-抗胰蛋白酶的浓度，从而增加患肺气肿的风险。α1-抗胰蛋白酶抗体（以1:9000稀释）可用作测定转基因表达水平的捕获抗体。它也可用于免疫电泳。兔抗α1-抗胰蛋白酶抗体可与人α1-抗胰蛋白酶发生特异性反应。
免疫原
纯化人 α-1-抗胰蛋白酶
應用
α1-抗胰蛋白酶抗体（以1∶1000稀释）可用于ELISA。它也可用于探测免疫印迹以鉴定A1AT。另外，它还可用于Ouchterlony双向扩散法。
兔抗 α1-抗胰蛋白酶抗体也可用于免疫电泳技术。
此抗体已成功使用的应用，以及相关的同行评审论文如下。
蛋白免疫分析（Western Blotting）（1篇文章）
蛋白免疫分析（Western Blotting）（1篇文章）
外觀
0.01 M 磷酸盐缓冲盐水 (pH 7.2) 冻干。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Mingming Gao et al.
Scientific reports, 9(1), 13427-13427 (2019-09-19)
Obesity and associated metabolic comorbidities represent a growing public health problem. In this study, we demonstrate the use of a newly created fusion gene of exendin-4 and α1-antitrypsin to control obesity and obesity-associated metabolic disorders including insulin resistance, fatty liver
Ronnie Lum et al.
The Journal of biological chemistry, 291(37), 19631-19641 (2016-07-15)
Calreticulin is a lectin chaperone of the endoplasmic reticulum that interacts with newly synthesized glycoproteins by binding to Glc1Man9GlcNAc2 oligosaccharides as well as to the polypeptide chain. In vitro, the latter interaction potently suppresses the aggregation of various non-glycosylated proteins.
James K Stoller et al.
American journal of respiratory and critical care medicine, 185(3), 246-259 (2011-10-01)
α(1)-Antitrypsin (AAT) deficiency is an underrecognized genetic condition that affects approximately 1 in 2,000 to 1 in 5,000 individuals and predisposes to liver disease and early-onset emphysema. AAT is mainly produced in the liver and functions to protect the lung
Joerg Schuettrumpf et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 13(1), 88-97 (2005-10-19)
Identifying factors that influence gene transfer efficacy is critical for a successful gene-based clinical study. Here we demonstrate that in vivo AAV-2-mediated gene transfer is efficiently inhibited by unfractionated heparin, but not by a heparin preparation containing mainly low-molecular-weight forms
Katarina Hajdin et al.
PloS one, 5(5), e10445-e10445 (2010-05-11)
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Improvement of treatment efficacy and decreased side effects through tumor-targeted drug delivery would be desirable. By panning with a phage-displayed cyclic random peptide library we selected a peptide with
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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