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Merck
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重要文件

92243

Sigma-Aldrich

胆固醇 N-(2-二甲基氨基乙基)氨基甲酸酯

≥98% (TLC)

同義詞:

3β-{N-[2-(二甲氨基)乙基]氨基甲酰基}膽固醇, DC-Chol

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About This Item

經驗公式(希爾表示法):
C32H56N2O2
CAS號碼:
分子量::
500.80
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.85

化驗

≥98% (TLC)

形狀

powder or crystals

官能基

ester

儲存溫度

−20°C

SMILES 字串

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4CC(CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)NCCN(C)C

InChI

1S/C32H56N2O2/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35)/t23-,25?,26+,27-,28+,29+,31+,32-/m1/s1

InChI 密鑰

HIHOWBSBBDRPDW-MTIZRNOUSA-N

應用


  • 白细胞介素6在阳离子脂质体诱导抗原特异性粘膜免疫球蛋白A中的作用。:本研究探讨了在阳离子脂质体中使用胆固醇N-(2-二甲基氨基乙基)氨基甲酸酯促进粘膜免疫球蛋白A的产生,突出了其在疫苗开发中的潜力(Tada et al., 2021)。

  • 鼻腔联合接种肺炎球菌表面蛋白A以及DOTAP和DC-chol组成的阳离子脂质体,可使小鼠获得抗原介导的抗肺炎链球菌感染的保护性免疫。:这项研究证实了胆固醇N-(2-二甲基氨基乙基)氨基甲酸酯在鼻腔疫苗中的效力,为预防呼吸道感染提供了一种有前景的策略(Tada et al., 2018)。


生化/生理作用

阳离子脂质体,在癌症基因治疗中进行研究,作为疫苗递送系统/佐剂

包裝

无底玻璃瓶。内含物装在锥底内插管中。

危險聲明

危險分類

Aquatic Chronic 4

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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