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72779

Sigma-Aldrich

三氯生

97.0-103.0% (active substance, GC)

同義詞:

三氯苯氧氯酚, 5-氯-2-(2,4-二氯苯氧基)苯酚, 氯苯酚

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About This Item

經驗公式(希爾表示法):
C12H7Cl3O2
CAS號碼:
分子量::
289.54
Beilstein:
2057142
EC號碼:
MDL號碼:
分類程式碼代碼:
51101500
PubChem物質ID:
NACRES:
NA.85

生物源

synthetic

品質等級

化驗

97.0-103.0% (active substance, GC)

形狀

powder or crystals

雜質

≤0.1% Water (Karl Fischer)

顏色

white

mp

55-59 °C

溶解度

1 M NaOH: 5% at 25 °C, faintly turbid to clear (colorless solution)

抗生素活性譜

fungi

作用方式

enzyme | inhibits

SMILES 字串

Oc1cc(Cl)ccc1Oc2ccc(Cl)cc2Cl

InChI

1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H

InChI 密鑰

XEFQLINVKFYRCS-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

化学结构式:二苯醚衍生物

應用

它是一种用于耶尔森菌(一种可能污染动物源食品的人类病原体)的头孢磺啶-氯苯酚-新生霉素选择培养基的组分。由于其抗原性低,irgasan 也是许多抗菌消费品的组成部分。

生化/生理作用

Irgasan 是一种广谱抗菌药物。它是细菌和 疟原虫中 II 类型脂肪酸合成酶 (FAS-II) 的烯酰-ACP(酰基载体蛋白)还原酶成分的抑制剂 。它也抑制哺乳动物脂肪酸合成酶 (FASN),并可能具有抗癌活性。

其他說明

将容器紧紧地封闭在干燥通风良好的地方。保存在干燥的地方。

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險聲明

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Environmental science & technology, 47(4), 1833-1843 (2013-01-17)
When discharged into surface waters via wastewater effluents, triclosan, the antimicrobial agent in handsoaps, and chlorinated triclosan derivatives (CTDs, formed during disinfection with chlorine) react photochemically to form polychlorinated dibenzo-p-dioxins. To evaluate the historical exposure of waters to these compounds
Joseph V Rodricks et al.
Critical reviews in toxicology, 40(5), 422-484 (2010-04-10)
Triclosan (2,4,4'-trichloro-2'-hydroxy-diphenyl ether) is an antibacterial compound that has been used in consumer products for about 40 years. The tolerability and safety of triclosan has been evaluated in human volunteers with little indication of toxicity or sensitization. Although information in
Z X Wang et al.
The British journal of surgery, 100(4), 465-473 (2013-01-23)
Surgical-site infections (SSIs) increase morbidity and mortality in surgical patients and represent an economic burden to healthcare systems. Experiments have shown that triclosan-coated sutures (TCS) are beneficial in the prevention of SSI, although the results from individual randomized controlled trials
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Journal of clinical periodontology, 31(12), 1029-1033 (2004-11-25)
To compare the effectiveness of triclosan/copolymer and fluoride dentifrices in improving plaque control and gingival health. We searched the Cochrane Controlled Trials Register, MEDLINE (1986 to March 2003) and EMBASE (1986 to March 2003). Personal files and the reference lists

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Information on fatty acid synthesis and metabolism in cancer cells. Learn how proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sources or are synthesized by the cell.

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