推薦產品
化驗
≥99.0% (HPLC)
形狀
powder or crystals
光學活性
[α]20/D −32±2°, c = 1% in H2O
雜質
~25% water
SMILES 字串
[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])([O-])=O)n2cnc3C(=O)NC=Nc23
InChI
1S/C10H13N4O8P.2Na.H2O/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
InChI 密鑰
KQCIGEIXDXQSGM-MSQVLRTGSA-L
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相關類別
應用
肌苷-5′-单磷酸盐 (5'-IMP) 可作为研究肌苷 5′ 的活性、特异性和动力学的底物-单磷酸脱氢酶 (IMPDH) 酶代码 EC 1.1.1.205，GMP 形成的限速酶和鸟嘌呤核苷酸池。
生化／生理作用
肌苷一磷酸或肌苷酸是次黄嘌呤的核糖核苷酸，是嘌呤合成过程中形成的第一个核苷酸。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Inosine 5′-monophosphate dehydrogenase activity as a biomarker in the field of transplantation.
Glander P, Hambach P, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry (2011)
Tomonori Nakanishi et al.
International immunopharmacology, 10(1), 91-97 (2009-10-21)
Inosine 5'-monophosphate dehydrogenase (IMPDH) inhibition is a critical target in solid organ transplantation, and the development of mycophenolate mofetil (MMF) represents a major advance in transplant medicine. In this study, the in vitro and in vivo pharmacological effects of BMS-566419
L Hedstrom et al.
Current medicinal chemistry, 18(13), 1909-1918 (2011-04-27)
Inosine 5'-monophosphate dehydrogenase (IMPDH) catalyzes the first committed step of guanosine 5'-monophosphate (GMP) biosynthesis, and thus regulates the guanine nucleotide pool, which in turn governs proliferation. Human IMPDHs are validated targets for immunosuppressive, antiviral and anticancer drugs, but as yet
Sofie Haglund et al.
Therapeutic drug monitoring, 33(2), 200-208 (2011-02-12)
There is a large interindividual variability in thiopurine metabolism. High concentrations of methylthioinosine-5'-monophosphate (meTIMP) and low concentrations of 6-thioguanine nucleotides (6-TGNs) have been associated with a lower response rate and an increased risk of adverse events. In this study, the
Chanporn Chaosap et al.
Food science of animal resources, 40(3), 338-349 (2020-05-20)
The effects of organic Zn-L-selenomethionine (Zn-L-SeMet) at 0.3 ppm on carcass composition, meat characteristics, fatty acid composition, glutathione peroxidase activity, and ribonucleotide content were compared against the commercial inorganic sodium selenite (Na-Se) and the combination of the two, in commercial
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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