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49409

Sigma-Aldrich

鬼笔环肽-Atto 488

BioReagent, suitable for fluorescence, ≥90% (HPLC)

同義詞:

Atto 488, Atto 488标记鬼笔环肽

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About This Item

分類程式碼代碼:
12161900
NACRES:
NA.25

產品線

BioReagent

品質等級

化驗

≥90% (HPLC)

形狀

solid

製造商/商標名

ATTO-TEC GmbH

&lambda ;

in water

紫外吸收

λ: 499-505 nm Amax

適合性

suitable for fluorescence

儲存溫度

−20°C

一般說明

Atto 488标记鬼笔环肽是一种具有高水溶性的亲水性荧光标记物。偶联至底物后,该荧光标记物携带-1的净电荷。在480-515nm的波长有效激发荧光。氩离子激光器的488 nm谱线适合激发Atto 488标记鬼笔环肽。

應用

Atto 488标记鬼笔环肽的结合性类似于天然的鬼笔环肽,可用于标记固定细胞中的F-肌动蛋白。鬼笔环肽标记物可定性和定量分析组织、细胞培养物或无细胞制品中的F-肌动蛋白。 由于Atto 488-鬼笔环肽荧光标记物不能穿入活细胞,比较适合用于鉴定破膜细胞。

特點和優勢

Atto 488-鬼笔环肽的特点:
  • 强吸收力。
  • 高荧光量子产率。
  • 高光稳定性。
  • 三重态极少。

法律資訊

本产品仅供研究使用。如果打算商业化,请联系知识产权持有者(德国ATTO-TEC GmbH公司)申请许可。

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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分析證明 (COA)

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Physical Review Letters, 98(21) (2007)
Christian Vogl et al.
The EMBO journal, 35(23), 2536-2552 (2016-07-28)
The transmembrane recognition complex (TRC40) pathway mediates the insertion of tail-anchored (TA) proteins into membranes. Here, we demonstrate that otoferlin, a TA protein essential for hair cell exocytosis, is inserted into the endoplasmic reticulum (ER) via the TRC40 pathway. We

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