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Merck
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Key Documents

482R-1

Sigma-Aldrich

p63 (EP174) Rabbit Monoclonal Primary Antibody

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About This Item

分類程式碼代碼:
12352203

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP174

描述

For In Vitro Diagnostic Use in Select Regions

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (482R-14)
vial of 0.1 mL concentrate, Research Use Only (482R-14-RUO)
vial of 0.5 mL concentrate (482R-15)
vial of 1.0 mL concentrate (482R-16)
vial of 1.0 mL concentrate, Research Use Only (482R-16-RUO)
vial of 1.0 mL pre-dilute ready-to-use, Research Use Only (482R-17-RUO)
vial of 1.0 mL pre-dilute, ready to use (482R-17)
vial of 25.0 mL pre-dilute ready-to-use (482R-10)
vial of 25.0 mL pre-dilute ready-to-use, Research Use Only (482R-10-RUO)
vial of 7.0 mL pre-dilute, ready to use (482R-18)
vial of 7.0 mL pre-dilute, ready to use, Research Use Only (482R-18-RUO)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))

同型

IgG

控制

lung (squamous cell carcinoma), prostate

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

nuclear

一般說明

p63 is a transcription factor that regulates many cell activities, including cell proliferation, maintenance, differentiation, adhesion, and apoptosis.1 It has been found to be a sensitive and specific marker of myoepithelial and basal cell populations in prostate, breast, skin, and salivary gland. Additionally, p63 has also demonstrated immunohistochemical utility in identifying benign and malignant breast lesions.2 In prostatic carcinomas, it can also be used to recognize benign glands adjacent to malignant glands.3 p63 can also be used to differentiate adenocarcinoma of the lungs, where it is usually negative, from squamous cell carcinoma, which can be useful for advanced stages of the carcinoma where surgery is no longer an option.4

品質

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2


分析證明 (COA)

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A Yang et al.
Molecular cell, 2(3), 305-316 (1998-10-17)
We describe the cloning of p63, a gene at chromosome 3q27-29 that bears strong homology to the tumor suppressor p53 and to the related gene, p73. p63 was detected in a variety of human and mouse tissues, including proliferating basal

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