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Key Documents

30549

Sigma-Aldrich

Kollicoat® IR

同義詞:

聚乙二醇-聚乙烯醇接枝-共聚物, 聚乙烯醇-聚乙二醇接枝-共聚物

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About This Item

CAS號碼:
分類程式碼代碼:
12162002
NACRES:
NA.25

雜質

ethylene glycol, complies (meets the requirements of Macrogol Polyvinylalcohol Grafted Copolymer Ph Eur Ed. 7)
≤1 ppm ethylene oxide
≤10 ppm dioxan
≤100 ppm vinyl acetate
≤15000 ppm acetic acid
≤20 ppm heavy metals

燃燒殘留物

≤2%

損耗

≤5% loss on drying

pH值

5.0-8.0 (20% in H2O)

黏度

50-250 mPa.s, 20 %(23 °C, Brookfield RVT) (SP.2, 100RPM)

酸值

10‑70 mg KOH/g

應用

Kollicoat IR在制药工业中用作粘合剂、粒料和颗粒物质。该研究等级产物只可用于 R&D和研发用途。

法律資訊

Kollicoat is a registered trademark of BASF SE

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Sandra Guns et al.
Pharmaceutical research, 28(3), 673-682 (2010-11-26)
To investigate the effect of the manufacturing method (spray-drying or hot-melt extrusion) on the kinetic miscibility of miconazole and the graft copolymer poly(ethyleneglycol-g-vinylalcohol). The effect of heat pre-treatment of solutions used for spray-drying and the use of spray-dried copolymer as
Susanne Muschert et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(1), 130-137 (2009-01-17)
The aim of this study was to better understand the underlying drug release mechanisms from aqueous ethylcellulose-coated pellets containing different types of drugs and starter cores. Theophylline, paracetamol, metoprolol succinate, diltiazem HCl and metoprolol tartrate were used as model drugs
Kyung Jin Son et al.
ACS applied materials & interfaces, 3(2), 573-581 (2011-02-05)
In this study, we describe the use of organized mesoporous titanium oxide (TiO(2)) films as three-dimensional templates for protein microarrays with enhanced protein loading capacity and detection sensitivity. Multilayered mesoporous TiO(2) films with high porosity and good connectivity were synthesized
Pan Liu et al.
Journal of pharmaceutical sciences, 101(8), 2811-2820 (2012-05-23)
The objective of this study was to investigate the drug release mechanism and in vivo performance of Tanshinone IIA sustained-release pellets, coated with blends of polyvinyl acetate (PVAc) and poly(vinyl alcohol)-poly(ethylene glycol) (PVA-PEG) graft copolymer. A formulation screening study showed

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