241R-4

Cyclin D1 (EP12) Rabbit Monoclonal Primary Antibody

• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100; 500
• 共軛: unconjugated
• 抗體表格: culture supernatant
• 抗體產品種類: primary antibodies
• 無性繁殖: EP12, monoclonal
• 描述: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 形狀: buffered aqueous solution
• 物種活性: human
• 包裝: vial of 0.1 mL concentrate (241R-44); vial of 0.5 mL concentrate (241R-45); bottle of 1.0 mL predilute (241R-47); vial of 1 mL concentrate (241R-46); bottle of 7.0 mL predilute (241R-48)
• 製造商／商標名: Cell Marque^™
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
• dilution: 1:100-1:500
• 同型: IgG
• 控制: mantle cell lymphoma
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 視覺化: nuclear
• 基因資訊: human ... CCND1(595)

描述

一般說明

Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. Cyclins are proteins that govern transitions through distinct phases of the cell cycle by regulating the activity of the cyclin-dependent kinases. In mid-to-late G1 phase of the cell cycle, cyclin D1 shows a maximum expression following growth factor stimulation. Anti-cyclin D1 has been successfully employed and is a promising tool for further studies in both cell cycle biology and cancer associated abnormalities. This antibody is useful for separating mantle cell lymphomas (cyclin D1 positive) from chronic lymphocytic leukemia/small lymphocytic lymphoma and follicular lymphomas (cyclin D1 negative). Hairy cell leukemia and plasma cell myeloma can weakly express Cyclin D1.

品質

IVD

IVD

IVD

RUO

聯結

Cyclin D1 Positive Control Slides, Product No. 241S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable