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重要文件

Y0000555

Iotrolan

European Pharmacopoeia (EP) Reference Standard

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About This Item

經驗公式(希爾表示法):
C37H48I6N6O18
CAS號碼:
分子量::
1626.23
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

iotrolan

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

SMILES 字串

Ic1c(c(c(c(c1C(=O)NC(C(O)CO)CO)I)C(=O)NC(C(O)CO)CO)I)N(C)C(=O)CC(=O)N(C)c2c(c(c(c(c2I)C(=O)NC(C(O)CO)CO)I)C(=O)NC(C(O)CO)CO)I

InChI

1S/C37H48I6N6O18/c1-48(32-28(40)22(34(64)44-12(4-50)16(58)8-54)26(38)23(29(32)41)35(65)45-13(5-51)17(59)9-55)20(62)3-21(63)49(2)33-30(42)24(36(66)46-14(6-52)18(60)10-56)27(39)25(31(33)43)37(67)47-15(7-53)19(61)11-57/h12-19,50-61H,3-11H2,1-2H3,(H,44,64)(H,45,65)(H,46,66)(H,47,67)

InChI 密鑰

XUHXFSYUBXNTHU-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Iotrolan EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

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[Prospects of the use of non-ionic X-ray contrast substances during endoscopic retrograde cholangiopancreatography].
N K Sviridov et al.
Vestnik rentgenologii i radiologii, (6)(6), 62-63 (2003-12-17)
W Krause et al.
Investigative radiology, 37(12), 698-705 (2002-11-26)
Use of near-infrared reflection spectroscopy (NIR-RS) as a new model to assess renal tolerance of contrast agents and determination of the effects of a prostacyclin analogue and of two phosphodiesterase inhibitors on renal tolerance. NIR-RS was used to measure total
Ingrid Böhm et al.
European journal of radiology, 55(3), 431-436 (2005-09-01)
To test whether mono- or dimeric X-ray contrast media (CM) may induce the de novo production of cysteinyl-leukotriens (cys-LT), that could contribute to allergic/allergy-like side effects. Leukocytes from 39 patients receiving iopromide or iotrolan for routine CT-examination were analyzed for
Ingrid Böhm et al.
Fundamental & clinical pharmacology, 25(2), 267-276 (2010-04-24)
The purpose was to analyze the influence of both mono-/dimeric X-ray contrast media (CM) and immunological co-factors on basophil degranulation. The study has been conducted in 31 adult patients who received nonionic CM injection for enhanced routine computed tomography examination.
Marc C Heinrich et al.
Radiology, 235(3), 843-849 (2005-04-23)
To compare the cytotoxic effects of dimeric and monomeric iodinated contrast media on renal tubular cells in vitro with regard to osmolality. LLC-PK1 cells were incubated with ioxithalamate, ioversol, iomeprol-300, iomeprol-150, iodixanol, iotrolan, and hyperosmolar mannitol solutions for 1-24 hours

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