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重要文件

Y0000269

Clazuril for system suitability

European Pharmacopoeia (EP) Reference Standard

同義詞:

Clazuril

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About This Item

經驗公式(希爾表示法):
C17H10Cl2N4O2
CAS號碼:
分子量::
373.19
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

clazuril

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

SMILES 字串

Clc1c(ccc(c1)[n]3nc[c]([nH][c]3=O)=O)C(c2ccc(cc2)Cl)C#N

InChI

1S/C17H10Cl2N4O2/c18-11-3-1-10(2-4-11)14(8-20)13-6-5-12(7-15(13)19)23-17(25)22-16(24)9-21-23/h1-7,9,14H,(H,22,24,25)

InChI 密鑰

QUUTUGLQZLNABV-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Clazuril for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

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分析證明 (COA)

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J Vercruysse
Avian diseases, 34(1), 73-79 (1990-01-01)
The efficacy of toltrazuril in comparison with clazuril on heavy experimental Eimeria labbeana and E. columbarum infections in pigeons was investigated. The minimum required dose of toltrazuril to completely suppress oocyst excretion is 20 mg/kg body weight for 1 day.
O Vanparijs et al.
Tijdschrift voor diergeneeskunde, 113(4), 190-194 (1988-02-15)
The effectiveness of clazuril (Appertex), a new anticoccidial agent for the treatment of pigeons is described in the present study. Clazuril, a benzene-acetonitrile derivative, is administered in a single dose. In laboratory studies, 121 carrier pigeons infected with E. labbeana
M Giorgi et al.
British poultry science, 49(5), 609-618 (2008-10-07)
1. Anticoccidials are widely used as food additives to prevent and treat coccidiosis. They are licensed for use in a prescribed concentration and during a specific time interval with broilers and pullets, but not for laying hens. 2. This study
L Maes et al.
Tijdschrift voor diergeneeskunde, 113(4), 195-204 (1988-02-15)
In a six-month study, the safety of repeated treatments with clazuril, a new anticoccidial agent for the treatment of pigeons, was evaluated during 4 to 5 consecutive reproduction cycles. Clazuril was administered weekly at the recommended therapeutic dose level of
W Coussement et al.
Research in veterinary science, 45(1), 117-119 (1988-07-01)
Racing pigeons were artificially infected with a mixed inoculum of Eimeria labbeana (85 per cent) and E columbarum (15 per cent) and treated orally with 2.5 mg clazuril either on day 1, 2, 3, 4, 5, 6 or 7 after

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