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Key Documents

Y0000042

Josamycin propionate

European Pharmacopoeia (EP) Reference Standard

同義詞:

Leucomycin V 3-acetate 4B-(3-methylbutanoate) 2A-propanoate

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About This Item

經驗公式(希爾表示法):
C45H73N1O16
CAS號碼:
分子量::
884.06
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

josamycin

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

格式

neat

運輸包裝

wet ice

儲存溫度

−20°C

InChI

1S/C45H73NO16/c1-13-34(50)59-42-38(46(10)11)39(61-37-24-45(9,53)43(29(7)56-37)60-35(51)21-25(2)3)28(6)57-44(42)62-40-31(19-20-47)22-26(4)32(49)18-16-14-15-17-27(5)55-36(52)23-33(41(40)54-12)58-30(8)48/h14-16,18,20,25-29,31-33,37-44,49,53H,13,17,19,21-24H2,1-12H3/b15-14+,18-16-

InChI 密鑰

NBWASFCRCRXRKF-HHKVLAKUSA-N

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Josamycin propionate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

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分析證明 (COA)

Lot/Batch Number

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M Ducci et al.
International journal of clinical pharmacology research, 4(3), 195-199 (1984-01-01)
In this study a new high-pressure liquid chromatographic method for monitoring plasma levels of josamycin is described. Josamycin propionate was used as the internal standard. After being extracted from plasma by chloroform at an alkaline pH, the compounds were easily
Cindy Govaerts et al.
Journal of mass spectrometry : JMS, 39(4), 437-446 (2004-04-23)
Coupled liquid chromatography and ion trap mass spectrometry (LC/MS) was used for the characterization of the semi-synthetic 16-membered ring macrolide josamycin propionate. On-line identification of impurities in this antibiotic complex was performed with an ion trap mass spectrometer without recourse
G Privitera et al.
International journal of clinical pharmacology research, 4(3), 201-207 (1984-01-01)
Josamycin propionate, a tasteless josamycin derivative suitable for the preparation of paediatric oral suspension, was employed in a large, multicentre clinical study aimed at evaluating the effectiveness and safety of the drug. Two hundred paediatric practitioners participated in the study

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