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Merck
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Key Documents

T35920

Sigma-Aldrich

p-甲苯磺酸 一水合物

ReagentPlus®, ≥98%

同義詞:

4-Methylbenzenesulfonic acid monohydrate, 4-Toluenesulfonic acid monohydrate, PTSA monohydrate, TsOH monohydrate

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About This Item

線性公式:
CH3C6H4SO3H · H2O
CAS號碼:
分子量::
190.22
Beilstein:
3568023
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

蒸汽密度

5.9 (vs air)

品質等級

產品線

ReagentPlus®

化驗

≥98%

mp

103-106 °C (lit.)

SMILES 字串

[H]O[H].Cc1ccc(cc1)S(O)(=O)=O

InChI

1S/C7H8O3S.H2O/c1-6-2-4-7(5-3-6)11(8,9)10;/h2-5H,1H3,(H,8,9,10);1H2

InChI 密鑰

KJIFKLIQANRMOU-UHFFFAOYSA-N

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相關類別

應用

在温和条件下,p -甲苯磺酸一水合物可作为 Friedel-Crafts 催化剂的更好替代品,用于芳香核与活化的烷基卤化物、烯烃或甲苯磺酸盐的烷基化反应。

法律資訊

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險分類

Aquatic Chronic 3 - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1C - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

8A - Combustible, corrosive hazardous materials

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Detailed characterization of p-toluenesulfonic acid monohydrate as a convenient, recoverable, safe, and selective catalyst for alkylation of the aromatic nucleus.
Mahindaratne MPD and Wimalasena K.
The Journal of Organic Chemistry, 63(9), 2858-2866 (1998)
Jhonny Azuaje et al.
ACS combinatorial science, 13(1), 89-95 (2011-01-21)
We document here the use of polymer-supported p-toluenesulfonic acid as a highly effective, robust, economical and eco-friendly isocyanide scavenger. The herein described strategy circumvent the intense and repulsive odor of volatile isocyanides, enabling simplified and odorless workup and purifications. The
Aditya Kulkarni et al.
Organic letters, 13(19), 5124-5127 (2011-09-10)
An environmentally benign procedure for the hydrogenation of unprotected indoles is described. The hydrogenation reaction is catalyzed by Pt/C and activated by p-toluenesulfonic acid in water as a solvent. The efficacy of the method is illustrated by the hydrogenation of
Koneni V Sashidhara et al.
Bioorganic & medicinal chemistry letters, 22(12), 3926-3930 (2012-05-23)
First synthesis of novel coumarin-trioxane hybrids is reported. The synthesis was achieved via condensation of β-hydroxyhydroperoxides with coumarinic-aldehydes in presence of p-toluenesulfonic acid in good yields and the novel hybrids were evaluated for their antimalarial activity both in vitro and
Daniel C Yee et al.
The FEBS journal, 280(22), 5780-5800 (2013-08-29)
Visual rhodopsins are recognized members of the large and diverse family of G protein-coupled receptors (GPCRs), but their evolutionary origin and relationships to other proteins are not known. In a previous paper [Shlykov MA, Zheng WH, Chen JS & Saier

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Separation of p-Toluenesulfonic acid (PTSA); Pyrimethamine

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