全部照片(1)
About This Item
經驗公式(希爾表示法):
C12H15N3O3S
CAS號碼:
分子量::
281.33
Beilstein:
677664
MDL號碼:
分類程式碼代碼:
12352119
NACRES:
NA.77
推薦產品
描述
Modulation and Signaling
品質等級
化驗
≥97% (HPLC)
形狀
solid
顏色
white to beige
適合性
HPTLC
儲存溫度
2-8°C
SMILES 字串
CCCS(=O)c1ccc2[nH]c(NC(=O)OC)nc2c1
InChI
1S/C12H15N3O3S/c1-3-6-19(17)8-4-5-9-10(7-8)14-11(13-9)15-12(16)18-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
InChI 密鑰
VXTGHWHFYNYFFV-UHFFFAOYSA-N
尋找類似的產品? 前往 產品比較指南
一般說明
Albendazole sulfoxide is a blood-brain barrier main metabolite of anti-parasitic agent albendazole that acts as a antihelminthic. It binds to colchicine binding site of β-tubulin and prevents polymerization. Albendazole sulfoxide exhibits greater affinity to parasitic β-tubulin than to mammalian.
應用
Metabolomics research
生化/生理作用
罗苯达唑是阿苯达唑的关键代谢产物,并作为驱虫药。研究表明,它可能通过使细胞周期停滞在 G2/M 期而诱导人癌细胞 HT-29 凋亡。
其他說明
For additional information on our range of Biochemicals, please complete this form.
訊號詞
Warning
危險分類
Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - Skin Sens. 1 - STOT RE 2 Oral
標靶器官
Adrenal gland,spleen,male reproductive organs,Blood
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Lidia Radko et al.
Journal of veterinary research, 61(3), 313-319 (2018-07-07)
Albendazole is used to treat endoparasitic diseases in animals and humans. After oral administration, it is quickly oxidised into its pharmacologically active metabolite albendazole sulfoxide and then to sulfone. However, it is not clear which compound is responsible for toxic
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務