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重要文件

RDD035

Sigma-Aldrich

HEPES钠盐 钠盐

≥99.5% (titration), free-flowing, Redi-Dri

同義詞:

4-(2-羟乙基)哌嗪-1-乙磺酸 钠盐, N-(2-羟乙基)哌嗪-N′-(2-乙磺酸) 钠盐

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About This Item

經驗公式(希爾表示法):
C8H17N2NaO4S
CAS號碼:
分子量::
260.29
MDL號碼:
分類程式碼代碼:
12161700
NACRES:
NA.25

產品線

Redi-Dri

品質等級

化驗

≥99.5% (titration)

品質

free-flowing

有用的pH值範圍

6.8-8.2

pKa (25 °C)

7.5

應用

diagnostic assay manufacturing

SMILES 字串

[Na+].OCCN1CCN(CC1)CCS([O-])(=O)=O

InChI

1S/C8H18N2O4S.Na/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1

InChI 密鑰

RDZTWEVXRGYCFV-UHFFFAOYSA-M

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一般說明

HEPES sodium salt is essential to prepare HEPES buffer that is commonly used for cell culture and protein applications. It is useful for maintaining homeostasis when working with cells outside of the incubator by balancing CO2. HEPES buffering capacity exceeds most buffers, with a pKa of 7.5, making it optimal for maintaining pH in biological systems. In solution, it is non-toxic, zwitterion with a physiological buffering range of pH 6.8 - 8.2. It has a low metal binding capacity and is safe to use in research for metal-binding proteins.

應用

HEPES sodium salt can be used:
  • as a protein precipitation buffer
  • in cell culture media
  • as a binding buffer

特點和優勢

  • Redi-Dri eliminates clumping for hygroscopic chemicals
  • powder remains free-flowing and easy to use
  • Safer to handle and weigh out for standard use in lab
  • Eliminates clumps, maintains product moisture, quality, and characteristics

外觀

冻干、喷雾干燥或结晶的材料。

其他說明

For additional information on our range of Biochemicals, please complete this form.

法律資訊

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Nishant Mehta et al.
Cell reports, 28(10), 2509-2516 (2019-09-05)
V-domain immunoglobulin (Ig) suppressor of T cell activation (VISTA) is an immune checkpoint protein that inhibits the T cell response against cancer. Similar to PD-1 and CTLA-4, a blockade of VISTA promotes tumor clearance by the immune system. Here, we report a
Åsa Birna Birgisdottir et al.
Autophagy, 15(8), 1333-1355 (2019-02-16)
Autophagosome formation depends on a carefully orchestrated interplay between membrane-associated protein complexes. Initiation of macroautophagy/autophagy is mediated by the ULK1 (unc-51 like autophagy activating kinase 1) protein kinase complex and the autophagy-specific class III phosphatidylinositol 3-kinase complex I (PtdIns3K-C1). The
Peng Yang
Macromolecular bioscience, 12(8), 1053-1059 (2012-06-19)
When lysozyme is dissolved in a neutral HEPES buffer solution (pH = 7.4) with 0.001-0.050 M TCEP added, a fast phase transition process occurs and the resulting novel fiber-like hierarchical supramolecular assemblies made by primary spherical-particle aggregation can function as a "superglue"
Hubert Gojzewski et al.
Scanning, 34(3), 159-169 (2011-09-29)
In this study, we deposited isolated magnetosomes from magnetotactic bacteria Magnetospirillum strain AMB-1 onto solid surfaces using spin coating (SC) and drop coating (DC) techniques. Four imaging techniques have been used to visualize the sample structure: scanning and transmission electron
Anca G Delgado et al.
Microbial cell factories, 11, 128-128 (2012-09-15)
Buffering to achieve pH control is crucial for successful trichloroethene (TCE) anaerobic bioremediation. Bicarbonate (HCO3-) is the natural buffer in groundwater and the buffer of choice in the laboratory and at contaminated sites undergoing biological treatment with organohalide respiring microorganisms.

文章

Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.

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