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重要文件

PHR1470

Supelco

东莨菪碱氢溴酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

同義詞:

东莨菪碱 氢溴酸盐

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About This Item

經驗公式(希爾表示法):
C17H21NO4 · HBr · 3H2O
CAS號碼:
分子量::
438.31
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to BP 199
traceable to Ph. Eur. H1500000
traceable to USP 1610001

API 家族

scopolamine, hyoscine

CofA

current certificate can be downloaded

包裝

pkg of 500 mg

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-30°C

SMILES 字串

Br.N1([C@@H]2[C@@H]3O[C@@H]3[C@H]1C[C@H](C2)OC(=O)[C@H](CO)c4ccccc4)C

InChI

1S/C17H21NO4.BrH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1

InChI 密鑰

WTGQALLALWYDJH-MOUKNHLCSA-N

基因資訊

human ... CHRM1(1128)

一般說明

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards
Scopolamine Hydrobromide is the hydrobromide salt of scopolamine, naturally found in belladonna plant. It belongs to the group of cycloplegic drugs, which produces cycloplegia. Its mode of action involves inhibiting the action of acetylcholine at muscarinic receptors in the ciliary muscle.

應用

Scopolamine Hydrobromide may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAB7821 in the slot below. This is an example certificate only and may not be the lot that you receive.

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

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存取文件庫

Topical Drug Bioavailability, Bioequivalence, and Penetration, 590(2), 341-353 (1993)
Dictionary of Optometry and Visual Science, 590(2), 341-353 (2014)
Comparison of isotachophoresis, capillary zone electrophoresis and high-performance liquid chromatography for the determination of salbutamol, terbutaline sulphate and fenoterol hydrobromide in pharmaceutical dosage forms
Ackermans TM, et al.
Journal of Chromatography A, 590(2), 341-353 (1992)
LC determination of atropine sulfate and scopolamine hydrobromide in pharmaceuticals.
Ceyhan T, et al.
Journal of Pharmaceutical and Biomedical Analysis, 25(3-4), 399-406 (2001)

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