PHR1402

盐酸酚苄明

Pharmaceutical Secondary Standard; Certified Reference Material

• 同義詞: 盐酸酚苄明 盐酸盐, N-(2-氯乙基)-N-(1-甲基-2-苯氧乙基)苄胺 盐酸盐
• 經驗公式（希爾表示法）: C₁₈H₂₂ClNO · HCl
• CAS號碼: 63-92-3
• 分子量：: 340.29
• EC號碼: 200-569-7
• MDL號碼: MFCD00055152
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823375
• NACRES: NA.24

屬性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to USP 1526007
• API 家族: phenoxybenzamine
• CofA: current certificate can be downloaded
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: Cl[H].CC(COc1ccccc1)N(CCCl)Cc2ccccc2
• InChI: 1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H
• InChI 密鑰: VBCPVIWPDJVHAN-UHFFFAOYSA-N
• 基因資訊: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

描述

一般說明

Phenoxybenzamine Hydrochloride is an important drug belonging to the class of β-chloroethylamine drugs. It functions as an α-blocker by binding to α-adrenoreceptors, located on vascular smooth muscles and stops the influence of sympathetic nerves on blood vessels. It is widely used in the treatment of hypertension, benign prostatic hyperplasia and hypoplastic left heart syndrome.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Phenoxybenzamine Hydrochloride may be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations by chromatographic and chemiluminescence techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

钙调蛋白拮抗剂；α-肾上腺素受体拮抗剂。

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA2196 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全資訊

• 象形圖: GHS08,GHS07
• 訊號詞: Warning
• 危險聲明: H302,H351
• 防範說明: P201 - P301 + P312 + P330 - P308 + P313
• 危險分類: Acute Tox. 4 Oral - Carc. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable