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重要文件

PHR1161

Supelco

普鲁卡因 盐酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

同義詞:

4-氨基苯甲酸-2-二乙氨乙酯, 奴佛卡因 盐酸盐, 对氨基苯甲酸二乙氨乙酯 盐酸盐

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About This Item

線性公式:
H2NC6H4CO2CH2CH2N(C2H5)2·HCl
CAS號碼:
分子量::
272.77
Beilstein:
3917802
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to USP 1564006

API 家族

procaine

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

155-156 °C (lit.)

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-30°C

SMILES 字串

Cl.CCN(CC)CCOC(=O)c1ccc(N)cc1

InChI

1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H

InChI 密鑰

HCBIBCJNVBAKAB-UHFFFAOYSA-N

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一般說明

Procaine hydrochloride is a synthetic compound that belongs to the class of local anesthetic drugs. It has a structure similar to the natural compounds that participate in nerve impulse transmission. It shows interaction with the cellular membranes causing membrane lipids to expand, membrane-bound calcium to displace and change the structure of the proteins that are responsible for regulating the cell permeability and shape.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Procaine hydrochloride can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrochemical, chemiluminescence, and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA7177 in the slot below. This is an example certificate only and may not be the lot that you receive.

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Skin Sens. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

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存取文件庫

Improved therapeutic index of cisplatin by procaine hydrochloride
Esposito M, et al.
Journal of the National Cancer Institute, 82(8), 677-684 (1990)
Colorimetric Determination of Procaine hydrochloride in Pharmaceutical Preparations using Diazotization Coupling Reactions
Al-Uzri WA and Al-Heeti MI
International Journal of PharmTech Research, 8(1), 1042-1042 (2015)
Electrochemical sensor for procaine based on a glassy carbon electrode modified with poly-amidosulfonic acid and multi-walled carbon nanotubes
Zhang X, et al.
Microchimica Acta, 169(1-2), 153-159 (2010)
Spectrophotometric Determination of Procaine Hydrochloride in pharmaceutical preparations Via Oxidative Coupling Reaction
Al-Abachi MQ, et al.
Tikret Journal of Pharmaceutical Sciences, 9(2), 213-222 (2013)
Batch and flow-injection spectrophotometric determination of procaine HCl in pharmaceutical preparations via using diazotization and coupling reaction
Al-Ward HS, et al.
Baghdad Science Journal, 9(3), 521-531 (2012)

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