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Merck
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重要文件

PHL82226

Cucurbitacin B

phyproof® Reference Substance

同義詞:

Amarine

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About This Item

經驗公式(希爾表示法):
C32H46O8
CAS號碼:
分子量::
558.70
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

primary reference standard

產品線

phyproof® Reference Substance

化驗

≥90.0% (HPLC)

製造商/商標名

PhytoLab

應用

food and beverages

形式

neat

儲存溫度

2-8°C

SMILES 字串

O[C@H]1[C@@H]([C@@]2([C@]([C@H]3[C@]([C@@H]4C[C@@H](C(=O)C(C4=CC3)(C)C)O)(C(=O)C2)C)(C1)C)C)[C@](O)(C)C(=O)\C=C\C(OC(=O)C)(C)C

InChI

1S/C32H46O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-13,19-22,25,34-35,39H,11,14-16H2,1-9H3/b13-12+/t19-,20+,21-,22+,25+,29+,30-,31+,32+/m1/s1

InChI 密鑰

IXQKXEUSCPEQRD-DKRGWESNSA-N

一般說明

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

法律資訊

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 2 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Dinia R Dwijayanti et al.
Phytotherapy research : PTR, 34(6), 1338-1346 (2019-12-18)
Bitter melon (Momordica charantia L.) is a vegetable and has been used as traditional medicine. Recently, we reported that bitter melon fruit extracts and its ethyl acetate (EtOAc)-soluble fraction markedly suppressed the expression of proinflammatory genes, including the inducible nitric
Li Yang et al.
Basic & clinical pharmacology & toxicology, 127(5), 371-379 (2020-05-27)
The present study investigated the improving effect of cucurbitacin B on liver fibrosis induced by concanavalin A in mice and explored its possible mechanism. AST, ALT and TB were detected by kits. ELISA was performed to detect the levels of
Jiaxin Xu et al.
Archives of biochemistry and biophysics, 684, 108314-108314 (2020-02-24)
Signal transducer and activator of transcription 3 (STAT3) is expressed aberrantly in multiple tumors, including gastric cancer (GC). STAT3 overexpression and excessive activation have been confirmed to play vital roles in tumorigenesis. Cucurbitacin B (CuB) is a natural product with
Jiangxia Du et al.
Toxicology letters, 338, 1-9 (2020-11-29)
Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor indicated for the first-line treatment of patients with metastatic or advanced non-small cell lung cancer (NSCLC) whose tumors have specific EGFR mutations. Pulmonary toxicity is one of the fatal
Yuki Yoshida et al.
BMC developmental biology, 19(1), 24-24 (2019-12-23)
Tardigrades are microscopic organisms, famous for their tolerance against extreme environments. The establishment of rearing systems of multiple species has allowed for comparison of tardigrade physiology, in particular in embryogenesis. Interestingly, in-lab cultures of limnic species showed smaller variation in

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