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Key Documents

P2307

Sigma-Aldrich

聚乙烯吡咯烷酮

suitable for plant cell culture, average mol wt 10,000

同義詞:

PVP, 聚维酮

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About This Item

線性公式:
(C6H9NO)n
CAS號碼:
MDL號碼:
分類程式碼代碼:
12352207
PubChem物質ID:
NACRES:
NA.71

形狀

powder

品質等級

分子量

average mol wt 10,000

技術

cell culture | plant: suitable

黏度號碼

12-18(lit.)

SMILES 字串

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI 密鑰

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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應用


  • Design and development of a soluble PDA-Emodin-PVP-MN patch and its anti-obesity effect in rats.: This study presents the development of a microneedle patch containing Polyvinylpyrrolidone (PVP), which enhances the delivery of anti-obesity medication, showcasing PVP′s utility in pharmaceutical formulations to improve drug solubility and efficacy (Wang H et al., 2024).

  • Polyvinylpyrrolidone Assisted One-Pot Synthesis of Size-Tunable Cocktail Nanodrug for Multifunctional Combat of Cancer.: This research demonstrates the role of PVP, as a stabilizer and regulator in the synthesis of a nanodrug cocktail, indicating its critical function in nanomedicine for targeting and treating cancer effectively, thereby optimizing therapeutic outcomes (Wang C et al., 2024).

  • Biochemical parameters, oxidative stress biomarkers, and anatomopathological changes in Wistar rats treated with 3′-demethoxy-6-O-demethylisoguaiacin and norisoguaiacin.: The study utilizes PVP in biomedical applications, particularly in enhancing the solubility and bioavailability of specific bioactive compounds for therapeutic purposes (Flores Jimenez NG et al., 2024).

  • A water-soluble preparation for intravenous administration of isorhamnetin and its pharmacokinetics in rats.: Highlighting PVP′s importance in creating water-soluble drug formulations that facilitate the intravenous delivery of hydrophobic substances, this study explores its application in improving drug delivery systems (Rassu G et al., 2024).

  • Activation of the PPAR gamma/NF-kB pathway by A-MPDA@Fe(3)O(4)@PVP via scavenging reactive oxygen species to alleviate hepatic ischemia-reperfusion injury.: This innovative study employs PVP to stabilize nanoparticle systems that actively participate in reducing oxidative stress, illustrating PVP′s potential in therapeutic interventions (Mo D et al., 2024).

其他說明

聚乙烯吡咯烷酮是 Denhardt′s 溶液的一种成分,在标准 50X 储备溶液中的浓度为 1%(w/v)。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Katja A Lüders et al.
Glia, 67(4), 634-649 (2019-01-15)
Proteolipid protein (PLP) is the most abundant integral membrane protein in central nervous system (CNS) myelin. Expression of the Plp-gene in oligodendrocytes is not essential for the biosynthesis of myelin membranes but required to prevent axonal pathology. This raises the
Abeer Maher Fayyad et al.
International journal of molecular sciences, 20(7) (2019-04-04)
Obesity is a major risk for diabetes. Brown adipose tissue (BAT) mediates production of heat while white adipose tissue (WAT) function in the storage of fat. Roles of BAT in the treatment of obesity and related disorders warrants more investigation.
Aaron R Jex et al.
Journal of clinical microbiology, 46(7), 2252-2262 (2008-05-02)
In the present study, we analyzed genetic variation in Cryptosporidium species from humans (n = 62) with clinical cryptosporidiosis in South Australia. Sequence variation was assessed in regions within the small subunit of nuclear rRNA (p-SSU), the 70-kDa heat shock
Nicole M Sanders et al.
American journal of physiology. Endocrinology and metabolism, 294(5), E853-E860 (2008-03-13)
Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed for patients with comorbid diabetes and depression. Clinical case studies in diabetic patients, however, suggest that SSRI therapy may exacerbate hypoglycemia. We hypothesized that SSRIs might increase the risk of hypoglycemia by
Doris Bach et al.
Journal of photochemistry and photobiology. B, Biology, 120, 74-81 (2013-03-08)
Photodynamic therapy (PDT) is a local tumour treatment accepted for a number of indications. PDT operates via the cellular stress response through the production of reactive oxygen species and subsequent cellular damage, resulting in cell death. Although PDT-induced signalling and

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