推薦產品
等級
analytical standard
品質等級
化驗
≥97.5%
形狀
powder
技術
HPLC: suitable
gas chromatography (GC): suitable
顏色
white
應用
forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products
格式
neat
SMILES 字串
[Cl-].C[n+]1cccc(c1)C(N)=O
InChI
1S/C7H8N2O.ClH/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H
InChI 密鑰
BWVDQVQUNNBTLK-UHFFFAOYSA-N
一般說明
1-甲基烟酰胺（MNA）是主要由烟酰胺N-甲基转移酶（NNMT）产生的烟酰胺的主要代谢产物，具有抗血栓形成和抗炎作用。
應用
1-甲基烟酰胺氯化物可用作使用离子对反相高效液相色谱法（RP-HPLC）定量尿液样品中1-甲基烟酰胺的标准品。
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
生化／生理作用
烟酸代谢的尿排泄产物
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
客戶也查看了
Stefan Chłopicki et al.
Pharmacological reports : PR, 64(2), 369-376 (2012-06-05)
Methylnicotinamide (MNA) displays vasoprotective activity, however, the regulation of the activity of nicotinamide-N-methyltransferase (NNMT), is largely unknown. We analyze a possible involvement of IL-6 in the activation of NNMT-MNA pathway during an endurance exercise. FVB, C57Bl/6J IL6(+/+) and C57Bl/6J IL-6(-/-)
Magdalena Sternak et al.
Pharmacological reports : PR, 62(3), 483-493 (2010-07-16)
Nicotinamide N-methyltransferase (NNMT), which converts nicotinamide (NA) to 1-methylnicotinamide (MNA), is up-regulated in the cirrhotic liver. Because MNA displays PGI(2)-dependent anti-inflammatory effects, the up-regulation of NNMT may play a regulatory role in liver inflammation. In the present work, we analyzed
Misha Patel et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 921-922, 87-95 (2013-02-26)
Nicotinamide N-methyltransferase (NNMT, E.C. 2.1.1.1) N-methylates nicotinamide to produce 1-methylnicotinamide. Enhanced NNMT activity is a feature of many types of cancer, and has been linked to processes such as tumour metastasis, resistance to radiotherapy and tumour drug resistance. As such
Tamara Kuchmerovska et al.
Neurochemistry international, 56(2), 221-228 (2009-10-20)
The present study has been designed to establish the potential benefits from 1-methylnicotinamide (MNA) treatment on brain disorders associated with type 1 diabetes. All experiments were carried out after 6 weeks of streptozotocin-induced diabetes (60 mg/kg of body weight, i.p.)
Wu-Ping Sun et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 35(2), 180-185 (2011-09-16)
Nicotinamide and catecholamines are both degraded by S-adenosylmethionine-dependent methylation. Whether excess nicotinamide affects the degradation of catecholamines is unknown. The aim of this study was to investigate the effect of nicotinamide on the methylation status of the body and methylation-mediated
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務