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重要文件

LIGHTOX14

Sigma-Aldrich

LightOx14

≥98% (HPLC)

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About This Item

經驗公式(希爾表示法):
C23H25NO2
CAS號碼:
分子量::
347.45
分類程式碼代碼:
12352101
NACRES:
NA.22

化驗

≥98% (HPLC)

形狀

powder

儲存溫度

2-8°C

SMILES 字串

N1(CCC(c2c1ccc(c2)C#Cc3ccc(cc3)C(=O)O)(C)C)C(C)C

InChI

1S/C23H25NO2/c1-16(2)24-14-13-23(3,4)20-15-18(9-12-21(20)24)6-5-17-7-10-19(11-8-17)22(25)26/h7-12,15-16H,13-14H2,1-4H3,(H,25,26)

InChI 密鑰

OCMSZODRCJAGHL-UHFFFAOYSA-N

應用

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

生化/生理作用

Strong ligand for retinoic acid receptor proteins

特點和優勢

LightOx14 is a synthetic analogue of all-trans-retinoic acid (ATRA) that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx14 can be utilized to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

其他說明

Chemical Equivalency 1ea=1mg

法律資訊

LightOx is a trademark of LightOx Ltd.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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文章

Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.

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