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Key Documents

C1510000

洗必泰

European Pharmacopoeia (EP) Reference Standard

同義詞:

1,1'-己基双[5-(对氯苯基)双胍]

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About This Item

線性公式:
[-(CH2)3NHC(=NH)NHC(=NH)NHC6H4Cl]2
CAS號碼:
分子量::
505.45
Beilstein:
2826432
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

chlorhexidine

製造商/商標名

EDQM

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

134-136 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)

InChI 密鑰

GHXZTYHSJHQHIJ-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Chlorhexidine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

象形圖

CorrosionEnvironment

訊號詞

Danger

危險聲明

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Matthias Maiwald et al.
PloS one, 7(9), e44277-e44277 (2012-09-18)
Skin antisepsis is a simple and effective measure to prevent infections. The efficacy of chlorhexidine is actively discussed in the literature on skin antisepsis. However, study outcomes due to chlorhexidine-alcohol combinations are often attributed to chlorhexidine alone. Thus, we sought
S Karki et al.
The Journal of hospital infection, 82(2), 71-84 (2012-08-15)
The topical use of chlorhexidine gluconate (CHG) is intended to reduce bacterial density on patients' skin. To assess the impact of body bath or skin cleansing with CHG-impregnated or CHG-saturated washcloths in preventing healthcare-associated infections and colonization. This systematic review
Carolyne Horner et al.
The Journal of antimicrobial chemotherapy, 67(11), 2547-2559 (2012-07-27)
Antiseptic agents are increasingly used for hand hygiene and skin decolonization as key tools for the prevention of healthcare-associated infections. Chlorhexidine, a divalent, cationic biguanide, has a broad spectrum of activity and is one of the most frequently used topical
Karl A Hassan et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(50), 20254-20259 (2013-11-28)
Chlorhexidine is widely used as an antiseptic or disinfectant in both hospital and community settings. A number of bacterial species display resistance to this membrane-active biocide. We examined the transcriptomic response of a representative nosocomial human pathogen, Acinetobacter baumannii, to
Steven P Engebretson et al.
JAMA, 310(23), 2523-2532 (2013-12-19)
Chronic periodontitis, a destructive inflammatory disorder of the supporting structures of the teeth, is prevalent in patients with diabetes. Limited evidence suggests that periodontal therapy may improve glycemic control. To determine if nonsurgical periodontal treatment reduces levels of glycated hemoglobin

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