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重要文件

77869

Supelco

(S)-(-)-α-甲基苄胺

for chiral derivatization, LiChropur, ≥99.0%

同義詞:

(S)-(-)-1-苯乙胺

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About This Item

線性公式:
C6H5CH(CH3)NH2
CAS號碼:
分子量::
121.18
Beilstein:
2204907
EC號碼:
MDL號碼:
分類程式碼代碼:
12000000
PubChem物質ID:
NACRES:
NA.22

等級

for chiral derivatization

品質等級

蒸汽壓力

0.5 mmHg ( 20 °C)

化驗

≥99.0% (sum of enantiomers, GC)
≥99.0%

形狀

liquid

光學活性

[α]20/D −30±1°, c = 10% in ethanol

光學純度

enantiomeric ratio: ≥99.5:0.5 (GC)

品質

LiChropur

技術

HPLC: suitable

折射率

n20/D 1.526 (lit.)
n20/D 1.528

bp

187 °C (lit.)

密度

0.94 g/mL at 25 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

C[C@H](N)c1ccccc1

InChI

1S/C8H11N/c1-7(9)8-5-3-2-4-6-8/h2-7H,9H2,1H3/t7-/m0/s1

InChI 密鑰

RQEUFEKYXDPUSK-ZETCQYMHSA-N

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一般說明

(S)-(−)-α-Methylbenzylamine is a chiral derivatizing agent, which is employed for derivatizing enantiomers into diastereoisomers.

應用

(S)-(−)-α-Methylbenzylamine may be used as a chiral derivatizating reagent for the determination of acetyl-D-carnitine (D-AC) in acetyl-L-carnitine (L-AC) using high-performance liquid chromatographic (HPLC) enantioseparation method.

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法律資訊

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

象形圖

Skull and crossbonesCorrosion

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Skin Corr. 1B

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 1

閃點(°F)

158.0 °F - closed cup

閃點(°C)

70 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Alejandra León et al.
Journal of natural products, 75(5), 859-864 (2012-05-12)
The enantiomeric lactams (-)-8, (+)-8, (+)-9, and (-)-9 were formed by the reaction of the dimeric phthalide rac-tokinolide B (rac-3) with (R)-(+)-α-methylbenzylamine and (S)-(-)-α-methylbenzylamine. The absolute configurations of compounds 8 and 9 were assigned by experimental and theoretically calculated electronic
Paul E Harrington et al.
Current medicinal chemistry, 14(28), 3027-3034 (2008-01-29)
The calcium sensing receptor (CaR) is a G protein-coupled receptor (GPCR) that plays a fundamental role in serum calcium homeostasis. The CaR is expressed on the chief cells of the parathyroid gland and is responsible for controlling the secretion of
Antoine Fadel et al.
The Journal of organic chemistry, 72(5), 1780-1784 (2007-01-30)
Enantiomerically pure (R)-(+)-pipecolic acid was synthesized in four steps and 42% overall yield starting from dihydropyran and (R)-alpha-methylbenzylamine. A general short strategy is also described for preparing (S)-proline (47.5% overall yield) and derivatives.
Carlos Fernandes et al.
The Journal of organic chemistry, 74(8), 3217-3220 (2009-03-17)
A short, convenient, gram scale protocol has been established to allow facile access to all four stereoisomers of 2-aminocyclobutanecarboxylic acid, each in enantiomerically pure form (ee >99%). Starting from the readily available cis racemate, the procedure combines efficient alpha-phenylethylamine derivative
Abraham R Martin et al.
Applied microbiology and biotechnology, 76(4), 843-851 (2007-06-22)
Enzyme immobilization often improves process economics, but changes in kinetic properties may also occur. The immobilization of a recombinant thermostable (S)-aminotransferase was made by entrapment on calcium alginate-3% (w/v)-and tested with (S)-(-)-(alpha)-methylbenzylamine for acetophenone production. The best immobilization results were

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