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Merck
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重要文件

51082

Supelco

溴己新 盐酸盐

analytical standard

同義詞:

2-氨基-3,5-二溴-N-环己基-N-甲基苄胺 盐酸盐, N-(2-氨基-3,5-二溴苄基)-N-甲基环己胺 盐酸盐, 溴苄环己铵 盐酸盐

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About This Item

經驗公式(希爾表示法):
C14H20Br2N2 · HCl
CAS號碼:
分子量::
412.59
Beilstein:
4848376
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

化驗

98.0-102.0% (AT)

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

SMILES 字串

Cl.CN(Cc1cc(Br)cc(Br)c1N)C2CCCCC2

InChI

1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H

InChI 密鑰

UCDKONUHZNTQPY-UHFFFAOYSA-N

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應用

Bromhexine hydrochloride may be used as a reference standard in the determination of bromhexine hydrochloride in:
  • Cough-cold syrup using high performance liquid chromatography (HPLC).
  • Pharmaceutical formulations using gas liquid chromatography (GLC) and high performance liquid chromatography (HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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Simultaneous determination of bromhexine hydrochloride and methyl and propyl p-hydroxybenzoate and determination of dextromethorphan hydrobromide in cough-cold syrup by high-performance liquid chromatography.
Rauha P-J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 15(2), 287-293 (1996)
Gas-liquid chromatographic and ion-pair high-performance liquid chromatographic determination of pseudoephedrine hydrochloride and bromhexine hydrochloride in pharmaceuticals.
Rao V E, et al.
Analyst, 112(6), 871-874 (1987)
Ryusuke Kajihara et al.
International journal of pharmaceutics, 481(1-2), 132-139 (2015-02-11)
Multiple-unit tablets consisting of polymer-coated microgranules and excipients have a number of advantageous pharmaceutical properties. Polymer-coated microgranules are known to often lose their functionality because of damage to the polymer coating caused by tableting, and the mechanism of polymer coating

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