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等級
analytical standard
品質等級
化驗
≥97.0% (HPLC)
儲存期限
limited shelf life, expiry date on the label
技術
HPLC: suitable
gas chromatography (GC): suitable
mp
203-205 °C (lit.)
應用
food and beverages
形式
neat
儲存溫度
2-8°C
SMILES 字串
COc1cc2C=CC(=O)Oc2cc1O
InChI
1S/C10H8O4/c1-13-9-4-6-2-3-10(12)14-8(6)5-7(9)11/h2-5,11H,1H3
InChI 密鑰
RODXRVNMMDRFIK-UHFFFAOYSA-N
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相關類別
一般說明
Scopoletin is a coumarin compound and pharmacologically active chemical that is found in various plant species.
應用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Scopoletin may be used as a reference standard for the determination of scopoletin in:
- Roots, stems, branches, and seeds as well as leaves of Chimonanthus nitens Oliv. by ultra-high performance liquid chromatography/tandem quadrupole-time-of-flight mass spectrometry (UHPLC-QTOF-MS/MS) equipped with modified mass deflect filter or diagnostic product ions/neutral loss filter.
- Canscora decussate (South Indian Shankhpushpi) extracts by high performance thin layer chromatography (HPTLC).
- Morinda tinctoria Roxb. leaf by HPTLC in conjunction with HPLC and gas chromatography with MS.
生化/生理作用
东莨菪素通过促进 LPL 基因的转录,显著增强脂肪细胞中脂蛋白脂肪酶的活性。它还部分逆转 TNF-α 对 LPL 的抑制作用。
包裝
Bottomless glass bottle. Contents are inside inserted fused cone.
其他說明
This compound is commonly found in plants of the genus: achillea angelica glycyrrhiza lycium pimpinella
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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HPTLC Finger print analysis and Phytochemical Investigation of Morinda tinctoria Roxb. Leaf extracts by HPLC and GS MS.
Arunachalam KD, et al.
International Journal of Pharmacy and Pharmaceutical Sciences, 7(2), 360-366 (2015)
Structural characterization and discrimination of Chimonanthus nitens Oliv. leaf from different geographical origins based on multiple chromatographic analysis combined with chemometric methods.
Huang WP, et al.
Journal of Pharmaceutical and Biomedical Analysis, 154(2-3), 236-244 (2018)
Comprehensive profiling and characterization of coumarins from roots, stems, leaves, branches, and seeds of Chimonanthus nitens Oliv. using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry combined with modified mass defect filter.
Tan T, et al.
Journal of Pharmaceutical and Biomedical Analysis, 141(2-3), 140-148 (2017)
Use of scopoletin to inhibit the production of inflammatory cytokines through inhibition of the I?B/NF-?B signal cascade in the human mast cell line HMC-1.
Moon PD, et al.
European Journal of Pharmacology, 555(2-3), 218-225 (2007)
Rapid validated high performance thin layer chromatography method for simultaneous estimation of mangiferin and scopoletin in Canscora decussata (South Indian Shankhpushpi) extract.
Sethiya NK, et al.
Revista Brasileira de Farmacognosia, 25(3), 193-198 (2015)
條款
Effective analysis of passion flower by HPTLC fingerprinting, in conjunction with a comprehensive range of related reference materials, enables fast and efficient identification of this plant material.
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