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Key Documents

201316

Sigma-Aldrich

喹哪啶红

Dye content 95 %

同義詞:

2-[4-(二甲基氨基)苯乙烯]-1-乙基喹啉碘化物

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About This Item

經驗公式(希爾表示法):
C21H23IN2
CAS號碼:
分子量::
430.33
Beilstein:
3798055
EC號碼:
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47

形狀

powder or crystals

品質等級

成份

Dye content, 95%

技術

titration: suitable

溶解度

ethanol: 1 mg/mL, clear, dark red

λmax

528 nm

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

room temp

SMILES 字串

[I-].CC[n+]1c(\C=C\c2ccc(cc2)N(C)C)ccc3ccccc13

InChI

1S/C21H23N2.HI/c1-4-23-20(16-12-18-7-5-6-8-21(18)23)15-11-17-9-13-19(14-10-17)22(2)3;/h5-16H,4H2,1-3H3;1H/q+1;/p-1

InChI 密鑰

JOLANDVPGMEGLK-UHFFFAOYSA-M

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應用

喹哪啶红已被用作α1-酸糖蛋白(AAG)的荧光探针。

生化/生理作用

喹哪啶红(2-(对-二甲基氨基苯乙烯基)喹啉乙硫醇)是一种非常暗红色或红黑色的粉末。它主要用于调节细胞增殖、与淀粉样蛋白积累有关的疾病的诊断试剂、检测酶活性和牙科漂白材料。此外,喹哪啶红还涉及异常性疼痛和病毒感染性疾病的治疗。在pH 1.4时其呈无色,在pH 3.2时呈红色。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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World Health Organization
The International Pharmacopoeia, 1 (2006)
H Imamura et al.
Pharmaceutical research, 11(4), 566-570 (1994-04-01)
We examined different fluorescent probes suitable for fluorometric determination of alpha 1-acid glycoprotein (AGP) in serum. Quinaldine red (QR) was shown to bind strongly and selectively to AGP. Taking advantage of the enhanced fluorescence of QR in the presence of
H Imamura et al.
Biological & pharmaceutical bulletin, 16(9), 926-929 (1993-09-01)
We attempted to develop a fluorescent probe superior to conventional ones (8-anilino-1-naphthalenesulfonate and auramine O) for use in the study of drug-binding sites on alpha 1-acid glycoprotein (AGP). It was found that quinaldine red (QR) strongly bound to AGP and
A I Ivanov et al.
Clinical and experimental medicine, 2(3), 147-155 (2002-11-26)
The acute-phase response alters the composition of carrier proteins in plasma, which may affect the blood deposition and transport of biomediators and drugs. The effect of the acute-phase response on the ligand binding ability of plasma was studied in leukemic
Paul Zuck et al.
Analytical biochemistry, 342(2), 254-259 (2005-06-14)
Miniaturization of high-throughput screening (HTS) assays has several obvious advantages, including increased throughput and lower cost by reduction in reagent consumption. Although absorbance assays are widely used in research laboratories, their application for HTS in a low-volume format has been

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