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Merck
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重要文件

07245

Sigma-Aldrich

4-氨基丁酸甲酯 盐酸盐

≥99.0% (AT)

同義詞:

4-Aminobutyric acid methyl ester hydrochloride, GABA methyl ester hydrochloride, Methyl 4-aminobutanoate hydrochloride

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About This Item

線性公式:
NH2(CH2)3COOCH3 · HCl
CAS號碼:
分子量::
153.61
Beilstein:
3558996
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥99.0% (AT)

形狀

crystals

反應適用性

reaction type: solution phase peptide synthesis

顏色

colorless

mp

120-125 °C (lit.)

應用

peptide synthesis

SMILES 字串

Cl.COC(=O)CCCN

InChI

1S/C5H11NO2.ClH/c1-8-5(7)3-2-4-6;/h2-4,6H2,1H3;1H

InChI 密鑰

WPGPRLVPWACBHW-UHFFFAOYSA-N

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象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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I N Tiurenkov et al.
Farmakologiia i toksikologiia, 49(6), 31-34 (1986-11-01)
In pentobarbital-anesthetized cats GABA methylester (MEG) and beta-phenyl-GABA methylester (MEF) administered intravenously in doses of 1/100, 1/30, 1/10 of LD50 and injected intracerebroventricularly in doses of 0.1 and 0.5 mg produce hypotension, These effects are significantly suppressed by picrotoxin. These
M Bianchi et al.
Biochemical pharmacology, 32(6), 1093-1096 (1983-03-15)
4-Aminobutyric methyl ester hydrochloride (GME) is able to cross the blood-brain barrier after intracardiac administration to the rat. GME has an LD50 of 1300 mg/kg in mice and 950 mg/kg in rats, exhibits an antiaggressive effect and is able to
Michael R Emmett et al.
The Journal of organic chemistry, 77(15), 6634-6637 (2012-07-11)
Cyclopropane hemimalonates, when treated with sodium azide, undergo a tandem ring-opening decarboxylation to produce γ-azidobutyric acids in good yields. These adducts were hydrogenated to form γ-aminobutyric acid (GABA) methyl esters.

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