SCC256

BPH-1 Human Benign Prostatic Hyperplasia Cell Line

The BPH-1 cell line is a well-established model for human prostate biology and widely used for investigation into the causes and potential treatments for prostatic disease.

• 同義詞: BPH-1 cells, Benign Prostatic Hyperplasia cells
• 分類程式碼代碼: 41106514
• NACRES: NA.81

屬性

• 應用: cell analysis

描述

一般說明

BPH-1 is an immortalized benign prostatic hyperplasia cell line that is a highly cited human model for prostate growth and physiology. Compared to prostate cancer cell lines, BPH-1 cells expressed increased levels of estradiol (E2) and aromatase, factors that have been implicated in BPH progression (2). BPH-1 cells share the cytokeratin profile of luminal epithelial cells and do not express androgen receptor or prostate-specific antigen (PSA) (3). BPH-1 cells express the proto-oncogene p53 and harbor several chromosomal structural rearrangements but are non-tumorigenic in nude mice (3). Source:The BPH-1 cell line was established from primary prostatic tissue from a 68-year-old patient and the cell line was immortalized with Simian virus 40 (SV40) large T antigen (3). BPH-1 cells contain a neomycin resistance cassette and are resistant to G418.

細胞系來源

Human, Epithelial Cells

包裝

≥1X10⁶ cells/vial

儲存和穩定性

Store in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.

其他說明

This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact licensing@emdmillipore.com.

免責聲明

This product contains genetically modified organisms (GMO).
Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable