推薦產品
無菌
non-sterile
製造商／商標名
MultiScreen®
技術
parallel artificial membrane permeation assay (PAMPA): suitable
板尺寸
96 wells
1 of 4
本產品 | SML2320 | SML2919 | N7662 |
|---|---|---|---|
| form powder | form powder | form film or powder | form solid |
| assay ≥98% | assay ≥98% (HPLC) | assay ≥97% (HPLC) | assay ≥95% (HPLC) |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C |
| solubility H2O: 20 mg/L, clear | solubility - | solubility - | solubility H2O: >5 mg/mL |
| shipped in wet ice | shipped in wet ice | shipped in - | shipped in - |
一般說明
Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.
MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.
Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput
Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1
PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3
MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.
Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput
Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1
PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3
MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
應用
Non-Sterile, reusable, sturdy device made of PTFE, acceptor plate for PAMPA assays, 1 plate
Research Category
Nucleic acid|Protein
Nucleic acid|Protein
外觀
Color Code:Not Applicable
其他說明
Automation Compatible:Yes
法律資訊
MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany
分析證明 (COA)
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