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MILLIPLEX^® Mouse Cytokine/Chemokine Magnetic Bead Panel II Premix Space Saver (Bulk) Packaging

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in mouse serum, plasma and cell culture samples.

• 分類程式碼代碼: 12161503
• eCl@ss: 32161000
• NACRES: NA.47

屬性

• 品質等級: 200
• 物種活性: mouse
• 製造商／商標名: Milliplex^®
• assay range: standard curve range: 1-5,000 pg/mL; (IFNγ); standard curve range: 12-50,000 pg/mL; (Exodus-2/CCL21/6Ckine); standard curve range: 12-50,000 pg/mL; (IFNβ1); standard curve range: 12-50,000 pg/mL; (IL-11); standard curve range: 12-50,000 pg/mL; (IL-20); standard curve range: 12-50,000 pg/mL; (MIP-3β/CCL19); standard curve range: 2-10,000 pg/mL; (IL-16); standard curve range: 2-10,000 pg/mL; (MCP-5/CCL12); standard curve range: 2-10,000 pg/mL; (MDC/CCL22); standard curve range: 2-10,000 pg/mL; (MIP-3α/CCL20); standard curve range: 2-10,000 pg/mL; (TARC/CCL17); standard curve range: 24-100,000 pg/mL; (Fractalkine/CX3CL1); standard curve range: 24-100,000 pg/mL; (IL-17A/F); standard curve range: 5-20,000 pg/mL; (Erythropoietin (EPO))
• 技術: multiplexing: suitable
• 相容性: configured for Premixed
• 檢測方法: fluorometric (Luminex xMAP)
• 運輸包裝: wet ice

描述

一般說明

Cytokines are immunomodulatory polypeptides that play key roles in both adaptive and innate immune responses. A generic term, “cytokines” includes myokines (produced by muscle cells), lymphokines (produced by activated Th cells), interleukins (acting as mediators between T cells) and chemokines (responsible for T-cell migration). One of the regulatory mechanisms of the immune system, cytokines act at the recognition, activation, or effector phases of an immune response, modulating the development and functional activities of the subtypes of T cells, B cells and myeloid cells. Consequently, research involving cytokines plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, especially those responses that make up the inflammatory process. In addition, the mouse model and mouse-to-human translational studies provide data essential to understanding the role of cytokines and immune response in both normal and disease states.

The MILLIPLEX^® Mouse Cytokine/Chemokine Bead Panel II Premixed 14 Plex, contains all the components necessary to measure the following 14 biomarkers using Luminex^® xMAP^® technology: Erythropoietin (EPO), Exodus-2/CCL21/6Ckine, Fractalkine/CX3CL1, IFNβ1, IFNγ, IL-11, IL-16, IL-17A/F, IL-20, MCP-5/CCL12, MDC/CCL22, MIP-3α/CCL20, MIP-3β/CCL19, TARC /CCL17. The kit uses a 96-well format, contains a lyophilized standard cocktail, two quality controls and can measure up to 38 serum, plasma, or cell/tissue culture samples in duplicate.

Panel Type: Cytokines/Chemokines

應用

• Analytes: Erythropoietin (EPO), Exodus-2, Fractalkine/CX3CL1, IFNβ1, IFNγ, IL-11, IL-16, IL-17A/F, IL-20, MCP-5/CCL12, MDC (CCL22), MIP-3α/CCL20, MIP-3β/CCL19, TARC/CCL17.
• Recommended Sample type: serum, plasma and cell culture
• Recommended Sample dilution: 1:2 dilution of serum and plasma. Tissue culture supernatant may require a dilution with an appropriate control medium
• Assay Run Time: overnight or one day
• Research Category: Inflammation & Immunology

其他說明

Please contact Technical Service for linearity of dilution.

Sensitivity: Refer to kit protocol for sensitivities of individual cytokines/chemokines.

法律資訊

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

安全資訊

• 象形圖: GHS06,GHS09
• 訊號詞: Danger
• 危險聲明: H302 + H332,H311,H317,H319,H411
• 防範說明: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3